Formulation Featured Articles
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SAR – Sequence-Activity Relationships for Efficient Protein Engineering
5/1/2023
As protein-based therapeutics gain traction in the greater market, innovative techniques aimed at their optimization have become a key driver for industry.
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Aldevron Announces Expansion Of mRNA Production Capability
5/1/2023
Aldevron, a leading global manufacturer of DNA, RNA and proteins used in cell and gene therapies and vaccine development, will expand its mRNA production capabilities to include lipid nanoparticle (LNP) encapsulation and aseptic fill-finish capabilities enabling mRNA cGMP manufacturing services from Master Cell Bank through to Drug Product.
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Nanoparticle Engineering Addresses The Challenge Of Poor Aqueous Solubility
3/24/2023
As pharma companies aim to overcome development obstacles, it is important to incorporate GMP expertise alongside novel technologies that can enhance the properties of APIs and dosage forms.
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Analytics And Bioassays Can Safely Fast-Track mRNA-LNP Drug Development
2/23/2023
One main mRNA technology challenge is the formulation of delivery systems like lipid nanoparticles (LNPs). Learn about evading impurities in lipids, the future of mRNA-based genomic medicines, and more.
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How Outsourcing RNA-LNP Production Can Have A Competitive Advantage
2/23/2023
Manufacturing RNA-containing LNPs demands specialized expertise Explore some of the challenges of RNA-LNP drug manufacturing and the advantages of outsourcing RNA-LNP formulations.
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LNP Formulation For mRNA delivery
2/15/2023
Microfluidic mixing is one of the most effective means to formulate LNPs for its scalability and reproducibility. Explore LNP formulation, polishing, sterile filtration of mRNA-LNPs, and more.
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mRNA: Challenges And Strategies Related To The DNA Template Process
2/15/2023
Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.
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Defining The RNA Therapeutics Industry In 2023
1/16/2023
Four executives outline which industry challenges, strategic considerations, and opportunities should be top of mind as RNA therapeutics companies establish their to-do lists for 2023.
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Drug Discovery And Screening, A Digital Era For RNA-LNP Therapeutics
11/21/2022
Learn about the key stages of drug discovery and screening as well as how to overcome bottlenecks in screening mRNA-LNPs to rapidly develop genomic medicines.
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The Expanding Patent Landscape For RNA-Based Therapeutics
11/16/2022
The COVID-19 pandemic thrust RNA-based therapeutics into the spotlight. Before that, only a handful had received regulatory approval. Why are RNA-based therapeutics seeing more patent activity now and how should biotech companies mitigate patent risks? Attorneys from Neal Gerber Eisenberg share their insights.