Bioprocessing Application Notes & Case Studies
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Transferring From Microfluidics To A Turbulent Mixer
4/18/2024
What solutions did the client featured in this case study find when they sought help in transferring their formulation process to a turbulent Impinged Jet Mixing (IJM)?
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Achieving a 21-Fold Increase in Plasmids
4/17/2024
This study compares a plasmid production process using differing shaker flasks to assess the cultivation similarities and contrasts, as well as total plasmid yields after plasmid purification.
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Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting
4/17/2024
This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression.
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Bakuchiol Synthesis Optimization In S. Cerevisiae During Scale Up From 250mL To 5L
4/15/2024
Explore the significance of cost-effectiveness in synthetic biology and the successful scaling up of a process involving S. cerevisiae for the production of bakuchiol.
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Simplifying CHO Cell Line Genetic Stability Testing
4/11/2024
Here, we describe the use of whole genome sequencing to perform a comprehensive assessment of genetic stability in clonally derived CHO cell banks using the Aptegra™ CHO genetic stability assay.
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Scaling Up mAb Process Development To A 5L Bioreactor
4/10/2024
This study, conducted with cloud-connected bioreactors designed to accommodate CHO cells, showcases this technology transfer by comparing results obtained from shake flask cultures at various scales.
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Optimized Performance Model For Yield And Quality Of The mRNA Product
4/9/2024
Optimize your mRNA production by identifying an optimum set of conditions for the IVT reaction that produces high-quality mRNA in high yield using a design of experiment (DoE) approach.
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Evaluating On-Target/Off-Tumor Effects Of Cancer Immunotherapies
4/9/2024
A promising class of engineered T-cell engaging bispecific antibodies (TCBs) is revolutionizing cancer treatment, but safety concerns persist. Organs-on-Chips offer a human-relevant solution.
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Exploring Neuroinflammation, Neurodegeneration With A Brain Organ-Chip
4/9/2024
Examine how Organ-on-a-Chip technology, accurately mimicking human neuroinflammation, offers promising human-relevant avenues for neurodegenerative disease research and therapeutic development.
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Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology
4/9/2024
See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine.