INSIGHTS ON DOWNSTREAM MANUFACTURING
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Risk Control | Bulk Filling Application
Learn about a bulk filling system that enables you to achieve risk control, accuracy, and superior product recovery in your fill and finish operations.
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AAV Titer Estimation With Mass Photometry
How do new mass photometers, featuring a new titer estimation tool, perform as a powerful analysis technique when used to evaluate the quality of AAV samples.
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AAV Analytics: Key Considerations When Developing A Clinical Program
Finding partners with the necessary skills to optimize AAV processes is crucial for minimizing risk. Explore key considerations for advancing your therapy from concept to commercialization.
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Bulk Filling Of Drug Substance | Accurate Aliquoting
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.
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Streamlining Single-Use Assemblies In The Bulk-Fill Step Of Downstream Processing4/24/2024
Single-use (SU) systems and components are growing in demand as they offer minimal contamination risk. Review a standardized SU assembly for bulk-fill processing that aims to improve efficiency.
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New Instrumentation Expands Sediment Velocity AUC’s Utility4/24/2024
Purified adeno-associated viruses (AAVs) are prepared as a variety capsid species that must be characterized and quantified to ensure safety and efficacy.
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Identify And Quantify AAV Fill States Using Analytical Centrifugation4/24/2024
Purified AAVs are prepared as a variety capsid species. To ensure gene therapy safety and efficacy, it is crucial to characterize and quantify those species.
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De-Risking The Aseptic Drug-Filling Process And Optimizing Production4/17/2024
Aseptic drug-filling poses significant risks for manufacturers that can increase costs and timelines. Leveraging proven expertise and efficiency can ensure the production of safe, efficacious products.
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Robust Development Of Downstream Process Technologies For AAV4/17/2024
The focus of this study was to optimize the three primary downstream processing steps for AAV particle purification utilizing a design of experiments (DoE) methodology and screening devices.
DOWNSTREAM MANUFACTURING SOLUTIONS
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Discover a specialized solution designed for the downstream processing of viruses and viral particles that integrates convective mass transfer, pseudo-affinity chemistry, and optimized elution conditions.
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SKU: 4486-13
Item Name: Bosch Capsule Filler, Model GKF1400
Category: Capsule Fillers/Encapsulators > Hard Gel Capsule Filler
Manufacturer: Bosch
Location: Cleveland, OH
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Sourcing NaCl solutions can help streamline your buffer preparation allowing you to focus on additional critical steps in your biopharmaceutical processes.
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Explore a reliable tool for mass photometry calibrations that offers maximum precision with minimum hassle.
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The SamuxMP Auto is the automated version of Refeyn’s solution for AAV characterization, autonomously measuring up to 24 samples in approximately 90 minutes. The instrument offers quick measurements of purity, aggregation and loading of AAV samples of any serotype – with high precision and reproducibility.