Explore the challenges of adding cryoprotectants, how they can help reduce the effects of harmful conditions like ice crystals, and the need for future stability studies and substitutes for toxic CPAs.

Explore safety measures for handling mAbs in production in order to meet strict requirements that prevent contamination, product loss and exposure to cytotoxic agents or radioisotopes.

The integration of single-use technologies in upstream and downstream bioprocessing stages has transformed bioprocess manufacturing by improving efficiency, reducing costs, and minimizing contamination risks.

This article explores the use of viral vectors in gene therapies, as well as factors that negatively effect them during manufacturing.

Innovative process solution provider Single Use Support continues to deliver strong organic growth, supported by an expansion in its employee base. With a successful year 2023 in the rear-view mirror, 2024 is already shaping up to be even better.

Explore the benefits of different freezing techniques for small batches and their ability to meet the specific requirements and characteristics of different drug substances.

As novel methods for vaccine development grow more important, global vaccine development trends are emerging in a way that could impact the vaccine market in 2024 and beyond.

See how adopting the standardized and fully automated processes of Industry 4.0 can contribute to your cost efficiency, patient safety, and sustainability in pharmaceutical manufacturing.

Single-use technology is playing a large role in increasing flexibility and reducing contamination risks for the biopharmaceutical industry. Take a deeper look into all of the advantages and challenges.

In order to advance viral vectors like AAVs, there's a growing need for technologies and platforms that facilitate reliable and safe handling all the way from production to shipping and storage.

How does this pivot to natural gas-driven refrigeration platforms in the pharmaceutical manufacturing arena pose challenges and is sustainable cryopreservation possible?

Take a closer look at the process of cryopreservation, which role it plays for cell banking, and which challenges have to be overcome to reach the successful cryopreservation of cells.

Compare sterilization methods for single use assemblies and determine which is best suited to meet the needs of your operations and final product.

Review important factors in cell viability and cell health and how this information is crucial to researchers and cGMP cell banking.

Learn about the crucial role vectors play in delivering genes, types of non-viral vectors, the challenges with non-viral vectors in gene therapy, and the advantages of lipid-based nanoparticles.

By following some of the best practices in freezing mRNA, you can effectively balance product quality, cost-effectiveness, process safety, and efficiency.

Single Use Support, leading provider of fluid management and freeze-thaw logistic solutions for the biopharmaceutical industry, is excited to announce its further expansion into the United States market.

Delve into the medical applications of lipid nanoparticles with a focus on their role in targeted drug delivery, particularly in cancer treatment, gene therapy, and vaccine development.

Take a look at how antibody drug conjugates are advancing oncology therapeutics and explore seven facts about them you probably didn't know.

What does it mean to embrace flexible process solutions and how can modular systems benefit your company?

While antibody drug conjugates (ADCs) are a promising alternative for cancer therapy, their high toxicity presents a lot of challenges for the scale-up and industrial production of ADCs.

Manufacturers at biotech and biopharma companies need help keeping up with continuously advancing novel treatments. Technologies that provide control over the freeze-thaw process offer solutions.

If you are looking for an alternative to spray drying for your bulk intermediates, there's a plate-based freezing and thawing system that may provide a controlled and uniform solution.

Check out adaptable and scalable single-use solutions and automated processes that improve efficiency, lower costs, and address human error and product loss in the pharmaceutical manufacturing process.

Explore freeze and thaw technology that is being used to prevent alterations in the drug substance through the minimization of protein aggregation.

Learn about hybrid solutions for drug freezing and thawing, control over freezing and thawing of bottles, and how single-use bags support the start of a change in bioprocessing technology.

Explore advanced fluid management for cell culture freezing, cell banking and cell therapy.

Learn more about cold storage solution for valuable bulk drug substances at biomanufacturing facilities.

Learn more about the application of ADCs, the challenges of manufacturing them, and tools for handling them in closed systems without exposing them to the environment.

Learn more about the challenge of controlling cryogenic freezing, especially with liquid nitrogen, and some innovative solutions being presented.

Learn about a high performing bulk filtration, filling and draining platform for primary packages such as single use bags, bottles and vials. 

Explore viral vectors, an indispensable means to modify the genetic material of human cells, and their future in gene therapy.

Explore ways to tackle the process step of freezing and thawing when it comes to manufacturing quality biopharmaceutical products, like ADCs, at scale.

Learn what makes controlled cryogenic freezing such a vital step in the cold chain of the majority of biologics and understand more about different ranges of temperatures and freezing performance.

Join the discussion on how a new proprietary cryoprotectant technology and our a plate-based freeze/thaw unit can be uniquely combined to prepare Cryopreserved Thaw and Use Cell Plates.

Learn how fluid management in biopharma has changed considerably in recent years, and what we do to stay ahead.

Read how single-use technologies and the modular design options they offer can meet the requirements of both laboratory- and bulk-scale production without the need for major adaptations.

Read how single-use technologies are making supply chains more efficient and reduce product loss by providing specific protective technologies, equipped with Pharma 4.0 mechanisms.

We review the pre-use post sterilization integrity testing process and how its compatibility with single-use technology offers advantages compared to stainless-steel systems.

Read how the implementation of Pharma 4.0 standards and SOPs aims to reduce the different types of human error through the automation of processes that have traditionally involved human performance.

These insights provide a brief primer on Pharma 4.0 and will convey the key principles of the digital revolution in the pharma sector.

This article will give an overview of the inline buffer dilution process and discuss its benefits compared to traditional formulation of buffer solutions.

Today's challenges require a move towards agility and change, especially in the biopharma industry. Old-established structures will need to be reconsidered or even restablished and renewed.

Controlling the freezing behavior of bulk drug substance is the ultimate goal in biopharma manufacturing. This study demonstrates the impact of ice front growth speed on scalability of freezing protein solutions.

Supply chain management for CGTs will become increasingly complex to sustain their specific requirements. A much-needed approach to solving problems related to supply chain management is the development of smart packaging and related smart technologies.

When it comes to saving a patient’s life, speed and safety are key – as is the safe handling of the matter, where special protective and coolable packaging play a crucial role.

There is no full Pharma 4.0 manufacturing in place yet, but there are first innovations to build on.

Cell and gene therapies yield a small volume of individualized product for each single patient. Loss of the shipment or damage to the transported goods have serious consequences for patients.

There is still potential product loss with unprotected single-use bags, and there are still human errors dampening the euphoria of single-use systems. Here's how to protect your product investment.

RoSS shells contain 3D foams to protect and immobilize the filled and frozen bags while transporting. In this study we tested the RoSS shell's influence on the sterility on ISO cleanrooms

Plate-based freezers enable control over the freezing and thawing no matter what volumes you freeze. Explore the advantages and functionality of Single-Use Bags.

Protect any single use bag with RoSS: Robust Storage and Shipping. The right material at the right place – what we can learn from oysters.

Flexibility - How to prevent being stuck in one single-use system for biopharmaceuticals.

Liquid bulk drug substance is of utmost value after manufacturing from Biopharma industries. The single use bag independent platform RoSS helps to avoid product loss through breakages through robust composition and makes it possible to introduce your flexible end-to-end solution in drug substance logistics.

We close the gap between downstream and the fill & finish process in the biopharma industry. On the basis of single-use bags, we offer biopharma companies access to a new and almost 100% secure logistics process for liquids.

For any single use bag and any freezing infrastructure freeze your drug substance/product without worries! The right material at the right place – what we can learn from oysters. Tough protected & tamper evident! The tried and tested single-use bag gets its 100% secure and compact shell.