Newsletter | March 20, 2024

03.20.24 -- Novel Approaches For Obtaining High-productivity Clones

SPONSOR

What analytics technologies, tools, and instruments do biopharma developers consider requisite in the buildout of a modern biologics/ATMP, manufacturing facility? How are those tools enabling the analytics and controls that are requisite to continuous manufacturing and advancing the industry toward “biopharma 4.0?” Join Bioprocess Online Live on March 27th to find out! Registration is free thanks to the support of Culture Bio.

FEATURED EDITORIAL

Novel Approaches For Obtaining High-Productivity Clones

Let's dig into cell line selection approaches, transposons to increase copy number for the gene of interest, and targeted integration to rapidly obtain high-productivity clones.

INDUSTRY INSIGHTS

Faster Determination Of Dynamic Binding Capacity

Streamline the downstream process using variable pathlength technology to determine the DBC of affinity chromatography resins to produce reliable data more effectively and efficiently.

5 Surprising Findings From OT Vulnerability Assessments

Explore operational technology (OT) vulnerability assessment findings that may be unexpected or unanticipated, and find answers to common questions about these assessments, penetration testing, and more.

Contamination Control Technologies And Minimizing Filter Plugging

Learn about the three most common sources of filtration failures and how to prevent these problems.

Aseptic Filling Operations: Keep In-House Or Outsource?

Pouring millions into the infrastructure and quality systems necessary to move away from manual filling is unrealistic and detracts from your strengths in drug development.

A Lean, Agile Business Model To Deliver High-Quality Oncologic Treatments

No two journeys through the drug pipeline are the same; the ability to leverage a variety of approaches for different products is what sets one lean biotech company apart.

Enabling Real-Time Process Control

Defined control strategies enable more intensified and stable cell culture processes such as perfusion which may see dramatically improved productivity.

Building Complexity In Organoid Models

Learn about the impact and advancing use of organoids on basic and translational research, as well as their potential in areas such as disease modeling and drug screening.

Developing Robust mRNA Processes In A cGMP Environment

Explore current and emerging technologies to optimize mRNA manufacturing, especially when considering commercial production and the validation of processes in a cGMP environment.

Future-Proof Your Aseptic Filling

Using the Cytiva SA25 Aseptic Filling Workcell, a standardized system designed with flexibility built in, ensures that companies can pivot between products quickly and adapt as manufacturing needs change.

Must Know Analytical Techniques For Biopharma Developers

See how today’s leading instrumentation helps researchers get crucial information faster so they can speed up biopharmaceutical development and get to clinical trials faster with more reliable products.

Downstream Processing In The Age Of Precision Medicine

Explore alternative processes and solutions being suggested to combat the bottleneck created by downstream processing that is seriously impacting the overall production of treatments and vaccines.

Analyzing The Process For Single-Use Prokaryotic Cell Cultivation

Aseptic risk management plays a crucial role in bioproduct safety and efficacy. Discover a process for single-use production and automation control logic that ensures stable and efficient production.

Osmolality Analysis In Bioprocessing: From Theory To Practice

Gain insight into the impact of osmolality in bioprocessing as well as its correlation with immunoglobulin G (IgG) production.

Data Modeling Best Practices And Pitfalls For Pharma 4.0

Explore best practices that serve as a guideline for commonly encountered data modeling challenges and how life sciences manufacturers can overcome them by leveraging an industrial DataOps solution.

Overcome Single-Use Customization Misconceptions

Single-use strategies and tools are constantly evolving to better serve industry needs, and adept solutions providers can help streamline development with simple, custom adaptations.

SPONSOR

Webinar: Expediting Biologics Drug Development: Downstream Strategies To Accelerate Preclinical Development Timelines

Join us as we explore the utilization of historical data in downstream processes to expedite rapid process development, discuss the implementation of effective strategies to shorten the timeline in technology transfer processes, and analyze case studies demonstrating the successful application of bispecific antibodies as demonstrated in real-world scenarios. Click here to learn more.

SOLUTIONS

Access To Medicine In A Way The Industry Hasn't Seen Before

Take The Right Step To Advance Your Molecule

Particle Control In Biopharmaceuticals

Mabion Capacity Update February 2024: Large Molecule

Streamlining Analytical Development With LabZient

Secondary Packaging For Every Single-Use Bag

Your Trusted Partner Of Choice For Prefilled Syringe Success

Hipersep Flowdrive Pilot Preparative HPLC Chromatography System

Connect With Bioprocess Online: