04.10.24 -- Considerations For Robust Implementation Of The Multi-Attribute Method

Learn about Limulus amebocyte lysate assays, steps of the pipetting procedure, and tips to follow in order to deliver consistent and reliable results.

Learn about the importance of stability experiments early in the antibody-drug conjugates (ADCs) development process and use the data to mitigate future stability problems.

This demonstration features three purification methods that provide alternative options to successfully purify a monoclonal antibody in under 30 minutes with yields greater than 95%

Combining high-productivity chromatography methods and SU affinity membranes delivers a viable alternative to the current packed bed Protein A capture techniques for intensified purification of mAbs.

Analyze a chromatography system's performance during column qualification and protein A purification of a monoclonal antibody (mAb) from clarified cell culture fluid (CCCF).

Learn in-depth about the development of a flow-through polishing step that employs hydrophobic interaction chromatography for the elimination of monoclonal antibody aggregates.

This expert discussion focuses on residual impurities for gene therapy drug products, risk assessment, and characterization of product-related impurities in LVV based gene therapy products.