Application Note

Combining Single-Cell Isolation And Microplate Imaging To Improve Cloning Efficiency

By Shan Liu, PhD | Senior Scientist | Molecular Devices

Cell Culture GettyImages-1286306609

Improve your cloning efficiency with higher assurance of clonality by using a combination of single-cell isolation and microplate imaging. The CloneSelect™ Single-Cell Printer™ Series addresses the shortcomings of limiting dilution and flow cytometry-based cell sorting by offering image-based evidence for clonality, fast and efficient singlecell deposition based on white light (c. sight and f. sight systems) or optional fluorescence (f. sight systems only), excellent post-deposit cell growth, minimal risk of cross-contamination, and extremely low cost for maintenance. Explore how the f. sight can significant improve single-cell derived clone throughput by 8-fold compared with limiting dilution.

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