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FOCUS ON UPSTREAM MANUFACTURING |
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By Business Of Biotech Podcast | The biotech community praises scientific novelty, but unfamiliarity can breed skepticism among investors. This biotech leader embraces both on the Business of Biotech. |
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| Cell Line Development For High-Titer Lentivirus Vector Production | Case Study | By Hairui Yang, Han Gao, Houliang Wei, Qinrui You, Guodong Jia, and Weiran Shen, OBiO Tech | A new method is being utilized to significantly enhance LV vector yield using engineered HEK293T cells and pave the way for more efficient and large-scale production of LV vectors. |
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| Mitochondria Transplantation Therapy Advancements | White Paper | By Jonathan Carson, RoosterBio | Did you know that mitochondrial transplantation therapies have already been tried in humans and that there’s a firm rationale for this biomedical technology? |
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| Platform For Stable LVV Production Cell Lines Yield LVV Titres | Poster | By M. Tridgett, M. Mulet, et al., WuXi Advanced Therapies | LVV manufacturing processes remain a significant hurdle for sponsors. Review the potential of a platform of packaging and producer cell lines designed to enhance LVV manufacturing efficiency. |
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| Achieving Unique Synergies In Antibody Expression | Poster | By Rachel Kravitz, Wendy Vredenburgh, Victoria Chrostowski and Greg Bleck, Catalent | This cell line development technology, when combined with a cell line selection platform, can shorten your timelines and generate productive, stable, high-expressing cell lines. |
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| Modeling And Online Estimation Of kLa And P/V | Application Note | By Mike Khor, Abhinav Malhotra, et al., Culture Biosciences | Explore continuous models of kLa and P/V in 250mL and 5L bioreactors in order to scale-up and compare bioreactor performance metrics. |
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| Transient Expression Technologies For Antibody Production | Poster | By Anthony Lauer, James Ludtke, Chuenchanok Khodthong, Shannon Bruse, and Laura Juckem, Mirus Bio | Review studies that showcase the potential of the CHOgro Expression System in early stage drug development, where high titer antibody production in suspension CHO cells is crucial. |
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