Newsletter | April 24, 2024

04.24.24 -- Improve Your Process Development To Accommodate Diverse mAbs

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Webinar: How To Follow Best Practices In Aseptic Sampling To Improve Quality In Bioprocessing

Save the date for May 7th for an online event with Sartorius. We'll review the critical aspects of aseptic sampling, discuss the appropriate circumstances and methods for sampling, and share the impact the sample container itself may have on assay results. Learn how to ensure the highest standards of quality and process control with Sartorius. Click here to learn more.

FOCUS ON DOWNSTREAM MANUFACTURING

Improve Your Process Development To Accommodate Diverse mAbs

To navigate the uncertainties of mAb therapeutic manufacturing and its business landscape with more precision and efficiency, sponsors and manufacturers are striving to better understand process development.

mRNA: Challenges And Strategies Related To The DNA Template Process

Encapsulated mRNA-LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

Detergent-Based Viral Inactivation

Need to change your viral inactivation method due to environmental concerns? Don’t underestimate how long it will take to change your process.

Quantifying Heterogeneous AAV Capsid Loading Using Mass Photometry

Quantifying the proportions of heterogeneously filled AAVs is a critical step in therapy characterization. This mass photometer is used to distinguish and measure heterogeneously filled AAVs.

Advancing Buffer Management And Single Use Inline Buffer Formulation

In this podcast, you will learn about the criticality of buffer to the biomanufacturing process as well as the challenges inherent to handling the sheer amount that is needed almost continuously.

Tips For Designing A Single-Use Manifold For Advanced Therapies

Expert single-use engineers address six common questions posed by cell and gene therapy manufacturers in the design of custom single-use manifolds for the critical handling of biological fluids.

What Are ADCs And How Do They Work Against Cancer?

Learn the basics of how ADCs are engineered and why that makes them such powerful tools to target cancers with precision.

NEW PODCAST EPISODE

Physician + Biotech Builder with Tome Biosciences' Rahul Kakkar, M.D.

Novel technologies aren’t interesting to Rahul Kakkar, M.D. unless they help patients. Sounds rational, but it’s a unique perspective in a platform-crazed biotech industry. Dr. Kakkar’s worldview is shaped by his work as a physician—work he continues even as he builds Tome Biosciences, where he serves as President & CEO. On Business of Biotech, Dr. Kakkar shares how his work as a physician informs his leadership, biopharma’s bad rap, and a whole lot more.

DOWNSTREAM MANUFACTUING SOLUTIONS

Protein Capture Devices For Antibody Purification - W.L. Gore & Associates

A Mass Photometer For AAV Analytics - Refeyn

Allegro™ Ready Filter Sets - Cytiva

Predicting CHO Retroviral Particle Clearance - Cygnus Technologies Inc.

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