Insights On Upstream Manufacturing
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Enhancing Development And Mitigating Challenges With Plasmid DNA
5/13/2024
Plasmids, essential in biologics manufacturing, pose challenges in their development and scale-up due to difficulties integrating and optimizing them with the appropriate cell lines during process development.
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Streamlining 3D Cancer Assays With Automated Innovations
5/13/2024
This article discusses the use of 3D cultured cancer models in the search for new therapies for complex diseases like cancer.
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Influence Of Peptones On CHO Glycosylation Profiles
5/10/2024
This study explores the impact of nutrient availability and complexity on the glycosylation profiles of monoclonal antibodies (mAb) produced by different CHO cell lines.
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A Different Approach To Adeno-Associated-Virus (AAV) Clarification
5/10/2024
Knowledge of the feed stream, process constraints, and goals, makes selecting depth and membrane filter combinations for preliminary bench-scale filterability studies possible.
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A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation
5/10/2024
Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.
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Evaluation Of AOF Peptones To Enhance Viral Vector Vaccine Production
5/10/2024
Explore the results of a study analyzing the use of peptones to improve the viral vector production process by enhancing cell growth.
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Explore A High-Performing Basal Medium And Feed Pairing
5/8/2024
A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
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6 Key Questions When Selecting Your Cell Banking Manufacturing Partner
5/8/2024
Evaluating a potential cell banking partner's experience, testing capabilities, and approach to material management can help guarantee the quality and consistency of your therapeutic cells.
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Viral Vector Producer Cell Lines: Learning From mAbs
5/7/2024
Learn how applying bioprocessing knowledge from the production of mAbs can accelerate the development of viral vector cell lines and improve efficiency in gene therapy manufacturing.
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How To Bring (Any) mRNA To Life: Simplifying Nucleic Acid Encapsulation
5/6/2024
New technologies for the encapsulation of nucleic acids, such as FDmiX, can potentially overcome limitations of currently available standard mixing technologies.