Bioprocessing Application Notes & Case Studies
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Optimize T Cell Phenotype With One-Step Isolation And Activation
5/10/2024
This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.
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Overcoming Rapid Growth Challenges With Process Liquid Preparation
5/10/2024
With a helpful assessment and the right process liquid preparation services, the CDMO featured in this study was able to find a path toward meeting the surge in demand for a client's therapeutic .
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A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation
5/10/2024
Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.
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Explore A High-Performing Basal Medium And Feed Pairing
5/8/2024
A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
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Accelerating The mAb Formulation Process
5/7/2024
Learn about a one-step process that was developed to streamline formulation, effectively reducing timelines from approximately 14 weeks to 8 weeks for this critical step.
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Advancing Cell Therapy Manufacturing: Rapid Sterility Testing
5/7/2024
The rapid sterility test kit used in the study was able to quickly detect bacteria and fungi in complex cell therapy product matrices, detecting six species listed in USP chapter <71>.
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Accelerate Process Development With Automated Aseptic Sampling
5/6/2024
Discover how implementing automated sampling systems enabled Takeda Pharmaceuticals to achieve new efficiencies in process development.
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Review Of Applications And Processes In Fixed-Bed Bioreactors
5/6/2024
Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.
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Lentiviral Vector Production Using Single-Use Bioreactors
5/6/2024
Here, we outline a scalable and robust upstream process developed for LVV production of HEK293T cells and demonstrate how to expand HEK293T suspension cells.
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Screening Peptones, Including “Titration And Blending” Protocol Examples
5/3/2024
Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.