Rapid Process Improvement Achieved By Applying A Rational Approach To Culture Media Optimization
The challenge of effective cell culture process development often involves how to simultaneously meet two competing needs: the need to maximize improvement of process performance and the need to minimize time spent on process development. By Tom Fletcher, Scott D Storms, and Jenny Y Bang, Irvine Scientific
WHITE PAPERS & CASE STUDIES
Effect Of Sterilization On Mechanical Properties Of Silicone Rubbers
Silicone rubber is widely used in the pharmaceutical industry where sterilizability is an essential requirement for all fluid transfer equipment. Pharmaceutical products must be sterilized frequently and repeatedly by high level energy and/or chemical vapor in order to eliminate bacterial surface contamination.
Guidelines For Efficient And Cost-Effective Scale-Up Filtration
Zeta Plus filtration media are widely accepted as the depth filters that meet more criteria of excellence than any comparable product. Their extensive use is a reflection of their versatility and consistent filtration performance. By 3M Purification Inc.
What Is A Particle Counter?
A particle counter is an electronic instrument that detects and counts airborne or liquid particles. Particles are detected using laser based optical systems that shine a powerful light through a detection chamber. By Dr. Hans-Walter Motzkus and Joe Gecsey
Improving DNA Removal from Bioprocess Purification Processes
Many new biological drug products produced using recombinant DNA technology, such as monoclonal antibodies, are produced in cell culture. Because therapeutic proteins such as monoclonal antibodies are produced in cell culture, impurities can result from the host cells, or cell substrates. By 3M Purification Inc.
Streamlining The Biological Factory: Making A Better CHO Cell For Biopharma Production
SAFC’s CHOZN® Platform has been developed as a ‘plug and play’ manufacturing system for the creation of biopharmaceutical producing cell lines.
Save Up To 8 Hours In Cell Line Development With ZFN Technology
Zinc finger nucleases (ZFNs) have proven to be a powerful tool for modifying genes. In comparison to traditional techniques, such as adding chemical or radiation based mutagens that cause various random mutations, ZFNs can create very accurate, targeted changes to the genome in a much more rapid fashion.