C18 Columns Expand Methods Development Toolbox
The flexibility to perform separations without pH, temperature or mobile phase restrictions arms chromatographers with powerful tools for tackling tough separations.
WHITE PAPERS & CASE STUDIES
Alternative Technologies For Cell Culture Clarification Efficiency
Production of therapeutics and diagnostics by cell culture processes has become the cornerstone of the biotechnology industry. Cell culture systems can consist of bacterial, yeast, insect or mammalian cells, with mammalian cell culture production becoming the most widely used method. By 3M Purification Inc
When Powders Fail To Flow
There are many traditional measurement methods for characterizing the “flowability” of powders: angle of repose, flow cup, tap test. Practitioners know that the information may not be useful some of the time, but experience helps to separate the meaningful test results from those that may be suspect.
Rapid Separation Of Basic Drug Compounds Under Alkaline pH Conditions On pH-Stable, Short .C18 Column
Mobile phase pH is a powerful tool in methods development, particularly for separation of neutral forms of amines or other organic bases under alkaline conditions. By Derek Jensen and Mark Carrier, Hamilton Company
Integrating Electronic Systems In The Clinical Trial Process
What exactly is an integrated electronic system for clinical trials? Though the term means different things to different people, there are some basic similarities on which the industry can agree
Quantitative Determination Of Bisphosphonate Pharmaceuticals And Excipients By Capillary IC-MS
Bisphosphonates are a group of compounds that are used as active pharmaceutical ingredients (APIs) to treat bone disorders including osteoporosis, Paget’s disease, and hypercalcemia. Typical methods for bisphosphonates analysis include liquid chromatography (LC) with derivatization and/or ion pairing, ion chromatography (IC), capillary electrophoresis (CE), and gas chromatography (GC) with derivatization. By Leo Jinyuan Wang and William C. Schnute, Thermo Fisher Scientific
MTOSoftgels - Providing Cohort Specific Hand Filled Softgel Capsules For Dose Escalation Studies
When a client needed to manufacture softgel capsule clinical supplies in a low cost, highly dose flexible manner, they turned to Velesco Pharmaceutical Services for MTOSoftgels.