Gaining Greater Predictability, Control And Quality In Bioprocessing With Metabolic Biomarkers
Biologics are an integral part of the landscape of current therapies as pipelines continue to fill with them. Due to their importance and this ever expanding pipeline, the demands continue to escalate due to cost pressure, competition, regulatory requirements, disposable systems, and biosimilars. To date, these demands arguably have primarily been met with empirical understanding. However, there is a critical need for new approaches, tools, and technologies to deliver deeper understanding beyond the empirical realm. By Dr. Kirk Beebe, Director of Application Science, Metabolon, Inc.
WHITE PAPERS & CASE STUDIES
An Environmental Life Cycle Assessment Comparison Of Single-Use And Conventional Bioprocessing Technology
Biopharmaceutical development and manufacturing demand scalable processes that can be smoothly transferred to production. These processes need to be quickly developed and easy to implement.
Are You Into Biosimilars?
Biosimilars are considered to be one of the fastest growing sectors of the pharmaceutical industry.
Supporting Advances In MAb Process Development And Manufacturing
GE Healthcare is a $17 billion unit of the General Electric Company (NYSE:GE), employing more than 46 000 people worldwide.
A Closer Look At BioPharmaceutical Equipment And Processes With Sartorius Team Members
Removing residual contaminants from a protein solution at large scale is rarely a straightforward process. Handling large process volumes and working with buffer conditions incompatible with downstream processing steps is costly and time consuming. Dilution and other steps to adjust conditions simply add time and cost to a process without improving the purity of the target molecule. By Gregory Krueger, Field Marketing Manager, Sartorius Stedim Biotech
Important Considerations For Implementing A Single-Use Biomanufacturing Strategy
Recent trends in biomanufacturing technology and the biopharmaceutical market are supporting the increased adoption of single-use (SU) manufacturing systems. On the demand-side, the biopharma industry is focusing on niche and rare diseases with smaller patient populations, resulting in the need for smaller, more agile biomanufacturing capacity. By Jodi M. Zobrist and Nicole W. O'Brien, Ph. D., Gallus Biopharmaceuticals, LLC
Automated pH Adjustment In An Intelligent Single-Use Mixing Platform
Most pH adjustment process steps in single-use biomanufacturing require manual manipulation of the product and vessel, including off-line sampling, pH measurement, and the addition of acid and base.