News Articles http://www.bioresearchonline.com/ 1/6/2009 10:00:00 AM Advaxis Inc (OTCBB: ADXS), a biotechnology company, received permission from the U. S. Food and Drug Administration (FDA) to test its lead drug candidate, Lovaxin C, in patients with grade 2/3 cervical intraepithelial neoplasia (CIN). With this approval of the Investigational New Drug (IND) application for Lovaxin C, the FDA "HOLD" on Advaxis' clinical program has been lifted. http://www.bioresearchonline.com/article.mvc/Advaxis-Phase-II-Clinical-Trial-HOLD-Lifted-0001?atc~c=771+s=773+r=001+l=a 1/6/2009 10:00:00 AM Cytori (NASDAQ: CYTX) today received U.S. Patent No. 7,473,420 (the '420 patent), which protects important formulations of the Celution® System output. This builds upon U.S. Patent No. 7,390,484, issued to Cytori in June 2008, which covers the Celution System technology for the bedside processing of stem and regenerative cells derived from adipose tissue. http://www.bioresearchonline.com/article.mvc/Cytori-Expands-Patent-Protection-for-Celution-0001?atc~c=771+s=773+r=001+l=a 1/6/2009 7:00:00 AM Sangamo BioSciences, Inc. , the leading developer of zinc finger DNA-binding proteins (ZFPs), recently announced an agreement to provide Pfizer Inc with a worldwide, non-exclusive license for the use of certain ZFP Nuclease (ZFNs) reagents to permanently eliminate the Glutamine Synthetase (GS) gene in Chinese Hamster Ovary (CHO) cell lines and for the use of these ZFN-modified cells for clinical and commercial production of therapeutic proteins. http://www.bioresearchonline.com/article.mvc/Sangamo-Biosciences-Announces-License-0002?atc~c=771+s=773+r=001+l=a 1/6/2009 2:40:00 AM RainDance Technologies, Inc., a provider of innovative microdroplet-based solutions for human health and disease research, recently announced that it has been selected to share in the first-ever round of cooperative research grants by The Massachusetts Life Sciences Center (MLSC). http://www.bioresearchonline.com/article.mvc/Raindance-Technologies-And-Harvard-University-0001?atc~c=771+s=773+r=001+l=a 1/5/2009 4:48:00 AM Scientists at the Stanford University School of Medicine and at UC-San Francisco have succeeded in isolating stem cells from human testes. http://www.bioresearchonline.com/article.mvc/Testes-Stem-Cell-Can-Change-Into-Other-Body-0001?atc~c=771+s=773+r=001+l=a 1/5/2009 2:54:00 AM Scientists from the Gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovered that a certain type of collagen, collagen VI, protects brain cells against amyloid-beta (Aß) proteins, which are widely thought to cause Alzheimer's disease (AD). http://www.bioresearchonline.com/article.mvc/Collagen-VI-May-Help-Protect-The-Brain-0001?atc~c=771+s=773+r=001+l=a 1/5/2009 2:40:00 AM Cancer and cell biology experts at the University of Cincinnati (UC) have identified a new tumor suppressor that may help scientists develop more targeted drug therapies to combat lung cancer. http://www.bioresearchonline.com/article.mvc/Cell-Biologists-Identify-New-Tumor-Suppressor-0001?atc~c=771+s=773+r=001+l=a 1/5/2009 2:32:00 AM Few things are as tiresome as house hunting and moving. Unfortunately, metastatic cancer cells have the relocation process down pat. http://www.bioresearchonline.com/article.mvc/Relocation-Plan-Of-Metastatic-Cancer-Cells-0001?atc~c=771+s=773+r=001+l=a 1/5/2009 2:02:00 AM Arizona Instrument LLC, an ISO 9001:2000 registered company, designs, manufactures, and markets the complete line of portable and fixed Jerome® toxic gas analyzers. http://www.bioresearchonline.com/article.mvc/Portable-And-Fixed-Jerome-Toxic-Gas-Analyzers-0001?atc~c=771+s=773+r=001+l=a 1/2/2009 11:01:00 AM Long-term gene therapy resulted in improved cardiac function and reversed deterioration of the heart in rats with heart failure, according to a recent study conducted by researchers at Thomas Jefferson University's Center for Translational Medicine. The study was published online in Circulation. http://www.bioresearchonline.com/article.mvc/Gene-Therapy-Reversed-Heart-Damage-In-Heart-0001?atc~c=771+s=773+r=001+l=a 12/31/2008 1:26:00 AM Using tiny gold particles and infrared light, MIT researchers have developed a drug-delivery system that allows multiple drugs to be released in a controlled fashion. http://www.bioresearchonline.com/article.mvc/Gold-Particles-Deliver-More-Than-Just-Glitter-0001?atc~c=771+s=773+r=001+l=a 12/30/2008 3:51:00 AM Researchers at The Ohio State University Comprehensive Cancer Center have discovered that a molecule implicated in leukemia and lung cancer is also important in muscle repair and in a muscle cancer that strikes mainly children. http://www.bioresearchonline.com/article.mvc/Study-Links-Molecule-To-Muscle-Maturation-0001?atc~c=771+s=773+r=001+l=a 12/30/2008 3:39:00 AM A new clinical trial suggests that long-term use of candesartan, a drug currently used to treat hypertension, may significantly reduce the symptoms of genetic heart disease. http://www.bioresearchonline.com/article.mvc/Safe-New-Therapy-For-Genetic-Heart-Disease-0001?atc~c=771+s=773+r=001+l=a 12/30/2008 3:14:00 AM A microscopic biological sensor that detects Salmonella bacteria in lab tests has been developed by an Agricultural Research Service (ARS) scientist and university colleagues. The sensor could be adapted to detect other foodborne pathogens as well. http://www.bioresearchonline.com/article.mvc/Nanotechnology-May-Be-Used-For-Food-Safety-0001?atc~c=771+s=773+r=001+l=a 12/30/2008 1:19:00 AM Aging yeast cells accumulate damage over time, but they do so by following a pattern laid down earlier in their life by diet as well as the genes that control metabolism and the dynamics of cell structures such as mitochondria, the power plants of cells. http://www.bioresearchonline.com/article.mvc/Both-Major-Theories-About-Human-Cellular-0001?atc~c=771+s=773+r=001+l=a 12/30/2008 12:59:00 AM New research in an animal model suggests that a diet high in inorganic phosphates, which are found in a variety of processed foods including meats, cheeses, beverages, and bakery products, might speed growth of lung cancer tumors and may even contribute to the development of those tumors in individuals predisposed to the disease. http://www.bioresearchonline.com/article.mvc/Common-Food-Additive-Found-To-Increase-Risk-0001?atc~c=771+s=773+r=001+l=a 12/30/2008 12:57:00 AM Cleveland BioLabs, Inc. recently announced several advances in the development of Curaxins, the leading class of drug candidates in the Company's anticancer drug discovery program. http://www.bioresearchonline.com/article.mvc/Cleveland-BioLabs-Reports-Advances-In-Curaxin-0001?atc~c=771+s=773+r=001+l=a 12/29/2008 11:21:11 PM It's not just patients with autoimmune diseases like lupus and rheumatoid arthritis (RA) that have self-attacking immune cells-healthy people have them too, according to a new report. http://www.bioresearchonline.com/article.mvc/Potential-Autoimmunity-Inducing-Cells-Found-0001?atc~c=771+s=773+r=001+l=a 12/29/2008 3:27:00 AM Scientists at the Hebrew University of Jerusalem have succeeded in reversing brain birth defects in animal models, using stem cells to replace defective brain cells. http://www.bioresearchonline.com/article.mvc/Hebrew-University-Scientists-Succeed-Through-0001?atc~c=771+s=773+r=001+l=a 12/28/2008 2:55:00 AM The Alzheimer's Drug Discovery Foundation (ADDF) announced recently that it provided a grant of $185,000 to Varinel, Inc., an emerging pharmaceutical company dedicated to developing drugs that can prevent neuronal degeneration and improve brain function. The grant will assist Varinel in advancing the preclinical development of its multifunctional lead compounds, VAR10300 (also known as M30). http://www.bioresearchonline.com/article.mvc/Alzheimers-Drug-Discovery-Foundation-Funds-0001?atc~c=771+s=773+r=001+l=a 12/25/2008 12:56:00 AM