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DGM Plate And Frame Filter Systems
•Datasheet: DGM Plate And Frame Filter Systems
With the Membraplan® DGM filter press system, a new generation of sheet filters was developed, setting new standards for modern pharmaceutical and biotechnological production. It can be used for a wide range of applications from initial cell harvest to down stream clarification steps.
The Membraplan DGM is a multiple sheet filter for filtration with depth filter sheets. It is the first system of its kind allowing for complete CIP cleaning and sterilization and thus meeting all requirements for pharmaceutical equipment.
The key to the success of the Membraplan DGM lies in the unique design of the filter plates. Each filter plate is sealed with an O-ring at the outer edge of the plate. This allows for zero leakage from the filter press during processing and CIP cleaning and eliminates any product contact with the surrounding environment.
The Membraplan DGM is available as a plate and frame (DG) or as a plate and frame with mechanical dehydration (DGM) design. The DGM version allows for mechanical squeezing of the filter cake with an elastic membrane thus increasing yields by reduction of moisture in the solids. This results in a dry and compact filter cake, which can be easily removed from the frame.
Features and Benefits
- Totally enclosed sheet filter system eliminating undesirable product loss
- Enclosed design allows for CIP cleaning and SIP* sterilization
- Mechanical dehydration (DGM) ensures higher yield and reduction of residual moisture in the filter cake
- Mechanical dehydration (DGM) allows for a dry compact cake in a short time when compared to typical gas drying
- Utilizes standard depth filter sheets for maximum selectivity
- Sizes from 300 x 300 mm (11.8 x 11.8 in.) to 1000 x 1000 mm (39.3 x 39.3 in.) for maximum scalability
- Cake washing plates available for maximum product recovery
- Can be equipped with automatic plate shifters and cleaning portals for 800 x 800 mm (31.4 x 31.4 in.) and 1000 x 1000 mm (39.3 x 39.3 in.) designs
- Filter plate and frames materials in USP certified polypropylene or 316 stainless steel
Applications
- Plasma fractionation
- Cell harvest
- Clarification of therapeutical proteins, vaccines, diagnostics, enzymes, and antibiotics
- Removal of activated carbon
- Activated carbon filter
- Removal of filter aids
- Removal of catalysts
Due to the enclosed design of the Membraplan DGM, for the first time a complete CIP cleaning can be carried out, which — in combination with manual precleaning — guarantees the reproducibility of the cleaning method by the FDA Inspection Guide on Cleaning Validation. The filer plate design was specially developed for strict requirements on hygiene and cleanliness in the biotechnological and pharmaceutical industry taking the recommendations and regulations of FDA, GMP and 3-A into consideration. Closing of the filter pack is carried out via hydraulic cylinder with mechanical locking.
The pneumatically operated hydraulics are installed on the cross member and are explosion proof as standard (no electrical components).
Click Here To Download:•Datasheet: DGM Plate And Frame Filter Systems
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