1. Hygienic Processing: Elimination Of Dead Space Volume

    Hygienic processing places high demands on the reliability and cleanability of production facilities. These requirements are especially high in separation processes like filtration and chromatography and are significant in ensuring purity of media by maintaining sterile process conditions.

  2. Single-Use Trends In The Life Science Industry

    At Interphex 2014, Todd and Todd interviewed Amber Sherrick, marketing manager with ASI Life Sciences, about the growing interest in single-use.

  3. Best Practices For Process Scale Column Packing Of CHT™ Ceramic Hydroxyapatite Media

    CHT ceramic hydroxyapatite media require specific considerations during process-scale chromatography packing due to high specific gravity, rapid settling rate, and sensitivity to mechanical shear.

  4. 3M Moves From Upstream Clarification To Improving Efficiencies In Downstream Purification

    At Interphex 2014, Todd and Todd interview Mark Trotter, Marketing Manager with 3M Purification.

  5. Design Of Experiments For Optimal Production Of Malaria Vaccines

    The aim of a joint project of the HAW Hamburg and the Biomedical Primate Research Center (BPRC) was to identify optimal protein expression conditions for high yields of potential malaria vaccines in the methylotrophic yeast Pichia pastoris.

  6. Online Glucose | Lactate measurement In Batch And Fed-Batch CHO Cultivation

    During the cultivation of animal cells the monitoring of nutrients and metabolites has an important role for the controlling strategy of the cell culture.

  7. Process Optimization Made Easy: Design Of Experiments With A Multi-Bioreactor System

    Design of experiments (DoE) is one of the most important techniques for systematic planning, execution and statistical evaluation of experiments.

  8. PAT-Enabled Process Optimization & Control

    PAT is a risk-based strategy for designing, analyzing and controlling manufacturing processes. The Critical Process Parameters (CPPs) are identified in line with the definition of the Critical Quality Attributes (CQAs) of intermediates or final products. PAT offers a number of tools for measuring and controlling these CPPs.
    Sartorius has the right choice of solutions you need: discover our world of Synchronized PAT Solutions.

  9. Automated Cell Dispensing And Image-Based Spheroid Formation Tracking

    Scientists using cell culture for drug discovery, toxicology, stem cell biology, and basic research realize the critical importance of 3-dimensional (3D) models. Data from cells cultured in a non-physiologic, monolayer format on plastic surfaces has long been suspected to differ from true in vivo physiology, and there is mounting evidence that this difference is slowing the pace of scientific discovery. By Brad Larson and Peter Banks, Applications Department, BioTek Instruments, Inc., and Nicky Slawny, 3D Biomatrix, Inc.

  10. Minitron Incubator Shaker

    With the launch of the Minitron incubator shaker, INFORS HT is following up on the worldwide success of the Multitron incubator shaker. The Minitron has the same outstanding characteristics as its big brother, the Multitron, but on a smaller scale.