SAFC^® at BioProcess International^TM 2011
Long Beach, CA October 31 - November 4

Feel Confident.
Empower your process development upstream and downstream

Visit us at Booth #301

Join us at IBC's BPI 2011 conference and learn how SAFC can provide solutions that add speed and efficiency to your biopharmaceutical manufacturing process:

• Bioprocess Liquid Manufacturing
  Learn about our tailored liquid solutions that bring compliance and flexibility to your bioproduction process.
  
  
• CHOZN GS Cell Line
  Find out more about our soon-to-be launched, first commercially available GS Knockout CHO Cell Line, which reduces production timelines, enabling you to take your molecule to clinic faster.
  
  
• Powder Transferred with Integrity^TM
  Effective containment and high product recovery with the efficiency of single-use technologies.

Workshops Overview

• "Mitigating the Risk of Viral Contamination, A Layered Approach"
  
  Building on its commitment to robust biomanufacturing solutions, SAFC, in partnership with Sartorius Stedim, is exploring technology to reduce the risk of adventitious virus contamination from raw materials used in upstream manufacturing processes. Developments in technologies such as HTST, UV-c irradiation and virus-retentive filtration will be presented as a layered approach to a robust risk mitigation strategy.
  
  Technology workshop by Wade Nudson, Manager, Technical Applications, SAFC & Sherri Dolan, Product Manager, Virus Clearance Technologies, Sartorius Stedim North America
  Tuesday, Nov. 1 at 11:45 a.m.
  
• "The CHOZN Platform: A Novel System to Enable Therapeutic Protein Manufacturers' Development"
  
  Abstract: To achieve biopharmaceutical industry levels of therapeutic recombinant proteins, SAFC has developed a new manufacturing platform process. This manufacturing platform system includes a novel CHO parental cell line as well as chemically defined medium and feeds that have been designed to work in harmony. The parental cell line is a CHO K1 glutamine synthetase (GS) knockout cell line engineered using Sigma-Aldrich's award winning CompoZr^® zinc finger nuclease (ZFN) technology. Harmonized medium and feed formulations were developed using chemically defined and animal component free raw materials that have a proven track record for sourcing and robust manufacturability. The CHOZN^® cell lines will be discussed, along with the subsequent CHOZN^® Platform.
  
  Technology workshop by Kevin Kayser, Associate Director, Cell Sciences and Development, SAFC
  Friday, Nov. 4 at 7:15 a.m. Continental breakfast provided at 7:00 a.m.
  

SAFC Recently Attended ESACT 2011
SAFC recently attended ESACT 2011 where they presented workshops and scientific posters that addressed issues the biopharmaceutical industry is facing in today's market and the innovative solutions SAFC can provide. Topics included:

• Risk Management in Biopharmaceutical Manufacturing
• SAFC's New Zinc Finger Nuclease CHOZN Cell Line Technology
• Sartorius Stedim Biotech Partnership with SAFC

View these dynamic presentations here

Feel confident. Experience peace of mind in your biopharmaceutical manufacturing process. SAFC is the custom manufacturing and services business unit of Sigma-Aldrich Corporation. We are recognized as a top 10 global fine molecule supplier and trusted manufacturer of specialty chemicals and biologics for the life science and high technology industries. Utilizing global "Centers of Excellence" and dedicated manufacturing facilities, SAFC can resolve development and manufacturing challenges and accelerate the production of custom materials. Our rich portfolio includes high-purity inorganic materials for high technology applications, cell culture products, services for biopharmaceutical manufacturing and biochemical production, and complex, multi-step organic synthesis of APIs and key intermediates. For more information about SAFC, visit www.safcglobal.com. Products/Services from SAFC for the Biopharmaceutical and Vaccine Industry: SAFC's platforms include proprietary serum-free and classical media, sera and specialty products such as buffers, detachment factors, growth factors and protein components, supplements and reagents. We offer unique services related to small volume custom media as well as single-use disposable bioprocessing systems that provide upstream and downstream solutions for biologic processes. We offer extensive regulatory, products and analytical support tied directly to customers' unique requirements. We have a proven track record in marketed biopharmaceuticals and are fully dedicated to customers' specific cell culture needs. SAFC likes to check periodically with you to verify that we have your accurate contact information. We want to make sure that you will receive the most up-to-date information. Click here to update your information.