OriGene Technologies uses high-throughput gene cloning and gene expression profiling to develop commercially available products for pharmaceutical, biotechnology, and academic research and discovery applications. Our flagship product is the cDNA clone collection, a searchable gene bank of over 30,000 human full-length TrueClone cDNA collection and over 25,000 TrueORF cDNA clones. In addition to cDNA clones, OriGene offers unique gene expression products such TissueScan cancer qPCR arrays for biomarker discovery and validation, and VERIFY™ Antigen Standards for antibody validation.

cDNA clones: Over-expression Expression-ready cDNA clones for gene function study. • TrueORF: ORF clones of highest QC level - Over 7,000 clones with Western data. - Over 30 destination vectors - GFP, RFP, YFP vectors New • TrueClone: Native protein expression	RNAi: Down-regulation          Potent 29mer shRNA against all human and mouse genes. • Pre-designed HuSH-29 shRNA   (New GFP Vector) • Custom Exact-shRNA service
Gene Expression    Expression level quantification/ profiling and biomarker validation. • TissueScan cancer qPCR arrays • Genome wide qPCR primer pairs New • qPCR template standards New • Human cancer tissue products	Proteins and Antibodies Comprehensive products for protein expression and detection. • VERIFY Tagged Antigen™   (over-expression lysate) • Antibodies Western Blot Guaranteed • Proteins

Featured new products

• New RFP, YFP vectors for flourescent tagging of 37,000 TruORF clones.
• OriGene released kinase deficient kinome including over 300 mutant clones as published in Cell
• OriGene expands qPCR offering - genome wide, pre-designed SYBR Green primers and template standards. Also 4 new TissueScan cancer qPCR panels.
• TrueORF expands utilities: The new destination vectors for bacterial expression is perfect for protein production in E.coli.
• OriGene Technologies Announces 37,000 ORF cDNA Clones in GFP Vector
• Exact-shRNA customize your shRNA solutions

OriGene Webinars

10,000 VERIFY Tagged Antigen™ As Western Blot Positive Controls and Antibody Validation (9 minutes 24 seconds) Cancer Gene Biomarker Validation via Unique TissueScan qPCR Arrays from OriGene Technologies (8 minutes 57 seconds) 37,000 TrueORFs and PrecisionShuttle Vectors (15 minutes 7 seconds)

Conferences
Where OriGene scientists are presenting their findings and new product launches

American Association of Cancer Research
April 18-22, 2009, Denver, CO Booth# 159

American Association of Immunology 2009
May 8-12, 2009, Seattle, WA Booth#121

2009 Biomedical Research Equipment and Supplies Exhibit at Harvard Medical School
September, 2009, Cambridge, MA

NIH Research Festival
October, 2009, Bethesda, MD

Neuroscience 2009
Oct 17-21, 2009, Chicago, IL

The American Society for Cell Biology
December 5-9, 2009, San Diego, CA

Origene Citations

Recent examples:
Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3ß in Mesangial Cells
Mitogen-Activated Protein Kinase Inhibition Induces Translocation of Bmf to Promote Apoptosis in Melanoma,
PTEN Loss Promotes Mitochondrially Dependent Type II Fas-Induced Apoptosis via PEA-15,
Retinoic Acid-induced Gene-1 (RIG-I) Associates with the Actin Cytoskeleton via Caspase Activation and Recruitment Domain-dependent Interactions

For more citations visit: www.origene.com/support/citations/citation.mspx?product=trueclone