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Poster: Influence Of Drying Method Of Carbonxymethyl High Amylose Starch (CM-HAS) Derivatives On Pysical Properties And Drug Release Profiles
By Marc Lemieux, Patrick Gosselin, and Mircea Alexandru Mateescu
There is a growing interest for biodegradable synthetic polymer used in oral controlled released drug delivery.
Carboxymethyl high amylose starch (CM-HAS) is able to control the drug release over 20h from monolithic tablet with 20 to 60% of drug loading and offers an gastric protection for oral formulation containing large and small molecules as well as microorganisms.
Drying processes have a significant effect on the physical and solid-state properties of materials and subsequent formulation characteristics.
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