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Article: Impact Of Cell Density And Viability On Primary Clarification Of Mammalian Cell Broth
Source:
BioProcess International
By Michael Iammarino, Joseph Nti-Gyabaah, Martin Chandler, David Roush, and Kent Göklen
Production of monoclonal antibodies from mammalian cell culture has become ubiquitous in the biotechnology industry as companies continue to identify opportunities to treat diseases with such therapeutic proteins. The first step in recovery of secreted antibodies is to remove most insoluble components of the cell culture from the product stream.
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