WAVE Bioreactor™ 500/1000 SystemSource: GE Healthcare Life Sciences
WAVE Bioreactor 500/100 system is part of GE Healthcare Life Sciences' ReadyToProcess platform of ready-to-use products. The system is a cell culture device for the production of recombinant proteins in mammalian and insect cell lines in batch, fed-batch, and perfusion culture. Culture medium and cells are loaded into a single-use, presterilized bag known as the Cellbag™ bioreactor. The Cellbag bioreactor is placed on an electric rocking base. The rocking motion of this base induces waves in the cell culture fluid within the Cellbag bioreactor to provide efficient mixing and gas transfer. The resulting environment within the Cellbag bioreactor can easily support 1 × 107 cells/mL. The Cellbag bioreactor requires no cleaning or sterilization, providing easy operation and protection against cross-contamination.
WAVE Bioreactor 500/1000 system delivers:
- Convenience: Presterilized, single-use Cellbag bioreactors protect against the risk of cross-contamination, require no cleaning, and involve minimal validation and they are supplied in a ready-to-use format
- Reliability: Cellbag bioreactors, including all fittings and filters, are supplied sterile and ready for use. They are suitable for cGMP commercial production and a biosafety cabinet is not required for inoculation or sampling
- Flexibility: Multiple instrument configurations for suspension, microcarrier, batch, fed-batch, or perfusion culture
- Versatility: The 500/1000 system is capable of handling culture volumes from 50 to 500 L