08.13.12 -- Understanding And Managing Cell Culture Contamination

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The BIOSTAT® B fermentor | bioreactor has been specially designed to cover the wide variety of requirements in biotechnological and biopharmaceutical research and development. BIOSTAT® B is the most successful autoclavable system of its class and is now available in the third generation. A wide range of configurations is available to choose from for animal, plant, and insect cell cultivation, as well as for microbial fermentation. Volumes range from 1 L to 2 L and from 5 L to 10 L. Learn more.

Featured Articles

Understanding And Managing Cell Culture Contamination
By John Ryan, Ph.D., Corning Incorporated
No cell culture problem is as universal as that of culture loss due to contamination. All cell culture laboratories and cell culture workers have experienced it. Culture contaminants may be biological or chemical, seen or unseen, destructive or seemingly benign, but in all cases they adversely affect both the use of your cell cultures and the quality of your research. 

A Single-Use Bioreactor For Both Cell And Microbial Cultures: A Dream Becomes Reality
By Nico M.G. Oosterhuis and Frank H. van Dongen, CELLution Biotech BV
Application of single-use equipment is common practice in the biopharmaceutical industrial and academic field. Compared to the traditional glass or stainless steel bioreactors, single-use bioreactors offer clear advantages.

Spotlight On Cell Culture

Finding Mutations In Cancer Cells Using Sunrise Absorbance Reader
Many diseases in humans are not caused by single genetic mutations; rather their outcome is influenced by complex interactions between environment, lifestyle, and genetic predisposition. On the other hand, there are many reports on the linkage between the prevalence of specific mutations and the outbreak of cancer.

Probing The CHO Genome And Gene Function Using ZFNs
Zinc finger nucleases (ZFNs) have proven to be a powerful tool for modifying genes. In comparison to traditional techniques, such as adding chemical or radiation-based mutagens that cause various random mutations, ZFNs can create very accurate, targeted changes to the genome in a much more rapid fashion.

Culturing Primary Chick Embryo Cells On A Thermo Scientific Nunc Nunclon Cell Culture Treated Surface
Thermo Scientific Nunc Nunclon cell culture products are tested for cell growth and plating efficiency using several different cell lines.

Comparison Of Five Cell Culture Media Demonstrating CHO Cell Culture Growth In Batch Or Fed-Batch Process For Commercial Operations
This case study details a two-month, four-phase project to design chemically defined feed media that improved two simulated batch processes utilizing products by SAFC, Life Technologies, Thermo Fisher Scientific, and Irvine Scientific.

Industry Webinar

Chromatography Column Packing For Manufacturing: The Benefits Of Dynamic Axial Compression
September 13, 2012 | 4:00 p.m. CET, 10:00 a.m. EST

Bio-Rad InPlace columns are designed to suit packing needs for pilot and manufacturing scale, and the packing protocols are directly scalable because the media bed is consolidated uniformly using axial compression. Join us in this technical discussion of current challenges and solutions for column packing and how Bio-Rad InPlace columns provide ease-of use and reproducible performance for process columns.
Register.

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