Trends And Challenges In Bioresearch: Managing Data And Navigating An Uncertain Regulatory Environment For Biotherapeutics Part III

By Tom Ricci

As the pharmaceutical industry pipeline continues to shift from traditional small molecule-based drugs to a new class of biologic therapeutics, bioresearchers need powerful bioanalytical techniques for the in-depth characterization of the protein of interest required at each development stage. The combination of modern UltraPerfromance Liquid Chromatography (UPLC) and Mass Spectrometry (MS) techniques have proven to provide researchers with the sophisticated tools they need to reliably characterize the large, complex molecules under investigation. Furthermore, software-driven informatics strategies provide bioresearchers with efficient tools to collect, mine, and analyze the massive amounts of raw data generated by these sophisticated instrumental techniques and convert it into actionable information.