Continuous chromatography first originated in the 1950s in the oil industry and has since become widely accepted for small molecule pharmaceuticals. Recently, biopharmaceutical manufacturers have begun to adopt the technology for the production of larger, protein-based drugs, a trend which should intensify as the industry continues to strive for more productive, cost-effective processes. Read more.
Hello New Selectivity
Introducing Nuvia™ cPrime™ media, the new hydrophobic cation exchange media that delivers unique selectivity for more purification power than ever before. With simpler method development and a wide design space, Nuvia cPrime lets you achieve a higher level of performance with a lot less compromise — so you can get to the clinic faster. Learn more.
Vydac Tech Poster: Reversed-Phase Scale-Up
By Reno Nguyen, Jochen Saar, Kim Vind, and Bart Denoulet
RP-HPLC is the preferred method for analyzing and purifying peptides and proteins. Pharmaceutical and biotech industries are working to optimize analytical separations of interest, including polypeptides. Read more.
UF/DF Systems Case Study
By Integrated Process Engineers & Constructors Inc. (IPEC)
Product is supplied to the UF/DF vessel from a chromatography system and then concentrated. When the target volume in the vessel is reached, the media is exchanged with a buffer through diafiltration. A control valve on the retentate side of the filters maintains a desired trans-membrane pressure (TMP). Read more.
Biopharmaceutical and biotech companies are assessing their current specimen management strategies to account for a changing ethical and regulatory environment and a lack of high-quality specimens. At the marcus evans Biobanking & Sample Management Strategies conference, delegates will learn to adopt innovative sample management practices to ensure current and future drug development is supported by high-quality samples. Learn more