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How Is Filtration Applied In Vaccine Production?
Vaccines are derived from a variety of sources including tissue extracts, bacterial cells, virus particles, recombinant mammalian, yeast and insect cell produced proteins and nucleic acids. Typically, vaccines are produced to treat the general population; however, vaccines can be tailored to treat specific individuals. Veterinary vaccines also have important economic significance in the protection of animal stocks. This Application Brief discusses the different adsorptive and exclusion based filtration separation technologies used in vaccine purification.
Learn more.
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Featured Articles
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PsiOxus' Brave Agenda To Destroy Cancer Cells
By Wayne Koberstein, contributing editor, Life Science Leader
PsiOxus is exploiting novel mechanisms to fight cancer directly, along with its indirect but lethal effects. In mid-July, the company landed funding for Phase I and II trials of ColoAd1, a "systemically available oncolytic vaccine" that selectively enters cancer cells and proliferates inside like a virus, killing the cells — an interesting marriage of targeted and immunotherapeutic strategies.
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Chromatographic Analysis And Characterization Of Protein-Based Drugs
By Tom Ricci
In the past five years, the commercial drug pipeline has made a dramatic shift away from conventional small-molecule drugs to biologic-based pharmaceuticals. This new class of protein-based pharmaceuticals is believed to be inherently safer than small-molecule drugs and will enable longer innovator exclusivity, because, today, it is not possible to create an identical copy of the drug, taking biogenerics out of the picture.
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Spotlight On Separation And Filtration
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Davisil® Technical Poster: Natural Product Purification
The reliable enrichment, analysis, and purification of low-abundance natural produce constituents from their complex crude extraction mixtures by liquid chromatography remains a key challenge in the pharmaceutical, food, flavors, and natural products fields.
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TETPOR HP Filter Cartridges Datasheet
TETPOR HP filter cartridges have been specially designed to minimize protein and preservative binding in the sterilization of pharmaceutical and multidose ophthalmic solutions.
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Capsules And Filters For Washwater Filtration
Sartobran P is the best choice for sterilizing-grade filtration of liquids requiring ultra low adsorption capabilities.
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ELx50 Microplate Strip Washer Datasheet
The ELx50 Microplate Strip Washer has a compact footprint and contains a powerhouse of washing capabilities unsurpassed in its class. The washer's excellent dispense precision and evacuation efficiency supports 96- and 384-well strip or plate washing, including ELISA, magnetic separation, and vacuum filtration washing applications.
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Upcoming Webinar
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The Impact Of Variability In Biopharmaceutical Manufacturing |
Americas: Oct. 25, 2012 2:00pm Eastern — Register
Europe: Oct. 25, 2012 4:00pm CEST — Register
In this webinar, we examine the impact of variability in biopharmaceutical manufacturing. Using real data, we suggest that variability is the single biggest issue facing biopharmaceutical manufacturers today, affecting not only unit operations but the entire supply chain design and management. The presence of significant variability requires systems that can 'sense and respond' in real time, so that issues can be resolved quickly and before they impact product quality. |
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Industry Event
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SLAS2013 |
January 12 to 19, 2013 | Orlando, FL
Join 4,500 of the best global laboratory science and technology minds. Access 130 outstanding podium presentations comprising 30 unique scientific sessions, more than 300 posters, and new and emerging technologies from more than 300 exhibitors from around the world. Experience the SLAS2013 community feel as you network and collaborate with friends old and new. |
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