Syloid® FP Silicas in Pharmaceutical Film Coatings

Film coatings are widely used in pharmaceutical oral dosage forms such as tablets, pellets, granules and drug crystals. Coatings are used for a variety of reasons including to mask tastes, improve stability, ease swallowing, assist identification, and more. Recently, film coatings have also shown encouraging results to enable the oral delivery of peptide therapeutics.

Syloid® FP silicas are used as excipients in many pharmaceutical formulations due to their unique morphology. The combined adsorption capacity, porosity, particle size and greater surface area allow them to provide several benefits simultaneously which can expedite manufacturing and improve efficacy of the final dosage form.

Syloid® FP silica can be used in polymeric coating systems and combined with cellulosic, vinylic, and acrylic-based polymers or combinations thereof. In these coatings in particular, Syloid® FP silica offers several benefits.

Syloid Silica Applications:

•  Anti-tacking agent
•  Oral peptide delivery
•  ODT formulations
•  Enteric coatings
•  Sustained release coatings
•  Controlled release coatings