Semi-Automated, Single-Use TFF Systems With An ‘Open Architecture' Design Maximize Flexibility And Allow Supply Chain Security
By Nick Hutchinson, Parker domnick hunter Process Filtration
Cross flow filtration used in bioprocesses is typically either microfiltration to clarify process streams or ultrafiltration to concentrate and diafilter the biopharmaceutical molecule. Single-use cross flow operations provide a number of advantages over traditional stainless steel systems. These include:
- Flexibility during process development
- Reduced capital investment
- Avoidance of cross contamination and faster product change overs
- Elimination of steaming and cleaning utilities
Parker domnick hunter’s innovative SciFlex® TFF system utilizes propriety technology allowing the sterile processing of biopharmaceutical product streams within an easy-to-learn and use system targeted at pilot plant operations and small scale manufacturing within the biopharmaceutical facility.