Mustang® XT Acrodisc® Ion Exchange Chromatography Units DatasheetSource: Pall Life Sciences - BioPharmaceuticals
Mustang XT Acrodisc units, available in Q and S chemistries, are idealfor scale—down process development work in a variety of downstream process applications. A membrane volume of<1 mL reduces the amount of sample required for evaluation, and the female luer lock inlet and outlet simplihes connection to typical low pressure chromatography systems. The open pore structure eliminates diffusion limitations of conventional macroporous allowing to access binding sites by convective flow. In addition, the large pores eliminate the size exclusion effect allowing full access to the binding chemistryforvery large proteins, plasmids and viruses.
Each unit contains 15 layers oflylustang membrane, exactlythe same as the largerhtustang units, allowing accurate scaIe—up from process devel pilot and process scale, especialtywith regards to flow/differential pressure and dynamic binding capacity.