Newsletter | May 21, 2014

05.21.14 -- Merck Assesses Single Use: Does It Make Sense At A Large Scale?

Bioresearch Online Newsletter
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Featured Content

From The Editor: Merck Assesses Single Use: Does It Make Sense At A Large Scale?
By Trisha Gladd, Editor, Pharmaceutical Online and Bioresearch Online
In an industry as conservative as the pharmaceutical industry, it is common practice to be adverse to new technologies because they are often viewed as too much of a risk. However, in this effort to play it safe, companies force themselves into a repetitive state of employing technologies that may not be the most efficient or effective. Rather than getting stuck in old habits — or conversely, jumping too quickly into new ones — Merck has put together a group of teams it calls the Technology Encouragement Collaborators, or TEC, to look at new technologies and determine whether or not to implement them.

From The Editor: Merck Assesses Single Use: Does It Make Sense At A Large Scale?

Article: Inflammation And The New Drug Development Paradigm
By Thomas Vihtelic, DVM, Ph.D., MPI Research
Opportunities abound for new treatments for inflammatory diseases, which afflict millions of people. Upward spiraling development costs, however, impede progress and delay relief for patients suffering from such debilitating diseases.


Article: The Art Of Optimizing Small Biotech Market Caps — From Scientific Dreams To Strategic Reality
Moderated and edited by Wayne Koberstein, Executive Editor
Last month, in Part One of this discussion, our panel of company executives and investment experts examined the key factors that can determine a small life sciences company’s valuation and market cap. As the sun rose outside the large meeting room window overlooking the San Francisco skyline, our roundtable — held during the confluence of industry events surrounding the JP Morgan Healthcare Conference in January 2014 — continued to explore the effects of valuation and market cap on such a company and what it can do to optimize its value at every stage of its development.


White Paper: Quantitative Determination Of Bisphosphonate Pharmaceuticals And Excipients By Capillary IC-MS
By Leo Jinyuan Wang and William C. Schnute, Thermo Fisher Scientific
Bisphosphonates are a group of compounds that are used as active pharmaceutical ingredients (APIs) to treat bone disorders including osteoporosis, Paget’s disease, and hypercalcemia. Typical methods for bisphosphonates analysis include liquid chromatography (LC) with derivatization and/or ion pairing, ion chromatography (IC), capillary electrophoresis (CE), and gas chromatography (GC) with derivatization.


Application Note: Optimization Of Monoclonal Antibody Production Employing Noninvasive Sensor Technology
By Sartorius Stedim Biotech
Large-scale, high-density fermentation and high-yield production of monoclonal antibodies are major aims of process development in the biopharmaceutical industry. On the other hand, there is an increasing demand for highly flexible and scalable production processes adapted to lab-scale, single-use culture vessels, i.e., to generate sufficient material for R&D or for preclinical applications.

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The Future Of Biosimilars: Addressing Regulatory Challenges
Date: Thursday, June 19, 2014 • Time: 1pm – 2:30pm EST

Featured Downloads

MPC/MPX Back-To-Back Body And Insert Adapters Specifications Sheet
MPC/MPX Back-to-Back Body and Insert Adapters from CPC give end users the flexibility of connecting off-the-shelf, single-use systems that feature identical coupling connections at the end of their tubing. CPC is the leader in the design and manufacture of single-use connection technology and connectors for the life sciences market, offering a wide variety of bioprocessing solutions including sterile connect, sterile disconnect, SIP connections, and quick connects.

ScreenFect A: DNA And siRNA Transfection Reagent
ScreenFect A is a transfection reagent composed of new cationic lipids selected by screening experiments by click chemistry.

Flexible Containment Solutions Guide: Drum Sampling Enclosure System
Sampling of active pharmaceutical ingredients, sensitizers, and other highly hazardous compounds for quality assurance purposes is a process that is performed on a routine basis.

Reduce Energy Utilization: Filtrete V-Bank Filters
Filtrete V-Bank Filters MERV A13 filters offer our customers a unique combination of performance and design features including integral gaskets and nested pleat packs.

imPULSE MDS: Mixing Platform
The imPULSE MDS platform has all the benefits and mixing capabilities of the imPULSE stationary platform except that the motor is mounted on the docking station allowing tanks to be easily interchanged. A loading/unloading hoist will ease the transfer of the shipping containers on and off the station.
Browse the download library

Featured Multimedia

Avoid Drug Shortages With Automation In Bioprocess
At Interphex 2014, Todd and Todd interview Todd Kapp, market development manager with Parker domnick hunter, to bring awareness to the solutions available in the bioprocess market.

Bulletin Board

MAb Manufacturing: Where Are We Headed, Cost Or Capabilities?
Following the discussion on monoclonal antibody (MAb) processing, partly conflicting observations can be made: Some push costs in the foreground of process technology discussion, while others emphasize robustness and peace of mind (low risk).

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Small-Scale Contract Freeze-Drying Services
Small-Scale Contract Freeze-Drying Services

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Biopharma Technology Limited

ARC Sensors: Integrate Into Process Control Systems
ARC Sensors: Integrate Into Process Control Systems

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Hamilton Company

Cadence Single-Use TFF Modules
Cadence Single-Use TFF Modules

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Pall Life Sciences - BioPharmaceuticals

Biopharm Technology Transfer And Development
Biopharm Technology Transfer And Development

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Therapure Biopharma Inc.

Single-Use Mixers
Single-Use Mixers

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Thermo Scientific

Chemically Defined Protein-Free Feed Medium: BalanCD CHO Feed 2
Chemically Defined Protein-Free Feed Medium: BalanCD CHO Feed 2

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Irvine Scientific

Stationary Cargo Tracking Devices
Stationary Cargo Tracking Devices

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LoJack SCI, Inc.

High Potency Products
High Potency Products

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Patheon Inc.