04.28.14 -- Live Cell Imaging of GPCR; Researchers To Test Drugs On Micro-Organs Instead Of Mice
Biologics Analysis Workflow™
Assess the purity of biologics efficiently and reproducibly in a cGMP-regulated environment with Bio-Rad’s Biologics Analysis Workflow. Leading labs are already using this validated workflow to increase throughput, simplify staining, and streamline imaging and data analysis. View the comparability study to see how easy it is to transition from your current analysis process. Learn more.
By Paul Held, Ph. D., and Peter Banks, Ph. D., BioTek Instruments, Inc.; and Paul Tewson, Anne Marie Quinn, and Thom Hughes, Montana Molecular
A significant proportion of academic and drug discovery research is devoted toward the elucidation of second-messenger signaling cascades resulting from interactions between G-protein coupled receptors (GPCR) and their ligands.
By K. John Morrow, Jr., Ph.D., and Ma Sha, Ph.D., Eppendorf, Inc.
Viral diseases, including rabies and influenza, are worldwide challenges to the international biomedical community. WHO notes that in 1998 more than 32,000 deaths due to rabies were reported, while influenza has been responsible for millions of deaths worldwide over the course of the past century.
A Q&A With Brent Bushnell, Bioprocess Applications Specialist, Colder Products Company
Closed single-use systems reduce the risk of two critical forms of contamination: biological contamination and cross-contamination. Biological contamination includes competitive organisms such as bacteria, fungi, and yeasts that are inadvertently introduced into cell culture processes. These organisms utilize culture nutrients, produce unwanted proteins, and limit growth or destroy the intended cell culture. Most biological contaminations result in rapid growth and observable culture changes that indicate a culture must be discarded.
By Yogesh Choudhari, Upendra Reddy, and Fred Monsuur, Grace
Recently, silica-based carriers have been widely used for the adsorption of oily and lipid-based formulations. Using silica as adsorbent, liquid self-emulsifying drug delivery systems could be formulated in tablet or capsule oral dosage form. For this application, an ideal carrier is one which possesses high adsorption capacity and immediate desorption or release at the desired site. Three different types of carriers, such as granulated fumed silica (GFS), syloid XDP-mesoporous silica gel (MSG), and magnesium aluminum silicate (MAS) were selected for this study.
By Dr. Frank Westad, Chief Scientific Officer, CAMO Software
Multivariate statistical process monitoring (MSPM) has been established as a valuable tool for ensuring reliable product quality in the process industry. However, many organizations today are still not fully utilizing its potential to make significant improvements in their production environment.
Gain the insight and contacts you need to make your single-use platforms more efficient, economical and meet more complex drug demands at IBC's 11th Single-Use Applications for Biopharmaceutical Manufacturing conference, taking place June 9-10 2014 in Boston, MA.
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