Product/Service

LiquiScan-ES Liquid Nanoparticle Sizing System

Source: TSI Incorporated
Liquiscan liquid nanoparticle sizer

The LiquiScan-ES system is an instrument designed for rapid, high resolution size analysis of nanoparticle colloids, proteins and other macromolecules.

The LiquiScan-ES system is an instrument designed for rapid, high resolution size analysis of nanoparticle colloids, proteins and other macromolecules down to 2.5 nm, and spanning a mass window of 8 kDa to >100 MDa. The power of the LiquiScan-ES system is its ability to analyze nanoparticles and macromolecules that are too large for mass spectrometry (MS), but with a level of accuracy and resolution not achievable via light-scatter based detectors. While other instruments used for sizing particles in liquids try to cover many magnitudes of size, the LiquiScan-ES focuses on superior performance over the nanoparticle size range generating research quality data.

The LiquiScan-ES Liquid Sample Nanoparticle Sizing System can be used for many applications:

  •  Macromolecule size analysis
  •  Protein and mixture separations
  •  Lipoprotein analysis
  •  Virus Identification
  •  Nanotoxicity
  •  Pharmaceutical R&D
  •  Investigations of colloidal aggregation and dissolution

Features and Benefits

  •  Size analysis down to 2.5 nm
  •  Mass analysis from 5 kDa to >100 MDa
  •  Single particle/molecule sizing using first principles
  •  Direct measurement of number size distributions
  •  High resolution sizing
  •  Fast measurement times
  •  Accurate measurements of multimodal distributions
  •  Enhanced sensitivity
  •  Independent of optical properties of solute or solvent
  •  Mature technology that is precise and repeatable
  •  Provides insights into aggregation of colloidal solutions
  •  Proven alternative to light scatter based techniques