By Fred Olds, Contributing Editor
"In today's world, a company can no longer be good at everything," says Hans Melotte, VP and chief procurement officer (CPO) at J&J. He says J&J came to realize that vertical integration no longer worked for them, and they needed to seek expertise through partnerships with outside entities. With tens of thousands of suppliers, horizontal integration posed a challenge to Melotte and his staff. His answer was standardization of their approach to suppliers and the development of business relationships with strategic suppliers.
By Tony Harrison, U.K. Subject Matter Expert to ISO Technical Committee 209 Working Group
The intensely manual practices of cleanroom classification and routine monitoring are time-consuming and prone to data errors. Particle counter performance and accuracy can vary widely, leading to inaccurate particle counting data.
By Brent Bushnell, Bioprocess Applications Specialist, Colder Products Company
This short, detailed Q&A provides information about combination connections and explains their use in single-use bioprocessing. It offers a guide on how single-use systems can be designed to integrate the combination connectors, and discusses applications that benefit from utilizing them.
By Ariette van Strien, Senior Vice President, Commercial Operations, Marken
The dramatic shift in our industry from small molecule drugs to high-value biopharmaceuticals is increasing the need to focus on logistics and supply chain management.
By Mark Mohr, CSafe Global
Healthcare product manufacturers, transportation providers, and distributors have a moral, and in most cases also a regulatory, responsibility to help ensure the product arrives to the end user intact. Protection of product efficacy demands use of the latest reliable technologies available. People's lives truly depend on it.
By Rakesh Bose, Scott Anderson, Kathy Lawrence, and Melissa Wilcox, Grace
Carbohydrates are commonly found as constituents in plants, animals, and microorganisms. Carbohydrate units have considerable applications in medicine when bound to lipids, peptides, proteins, or even nucleic acids. Total synthesis of bioactive natural products, amino glycoside antibiotics, glycodrugs, and glycoconjugate vaccines from carbohydrates have been of considerable interest in the medicinal field for a cure. Due to their therapeutic effects, conjugation of carbohydrates, and their presence in antibiotics, can be effectively used to find cures for the treatment of various diseases. Given their clinical importance in glycomics, synthesizing and purifying such molecules has been a challenge to synthetic chemists.