Newsletter | December 12, 2012

12.12.12 -- How Flash Chromatography Increases Peptide Purity

Bioresearch Online
How Flash Chromatography Increases Peptide Purity
By Jeff Horsman, Kathryn Lawrence, Bopanna N.K., Chitra Sundararajan, Melissa Wilcox, Grace; Janos Varga, Fabio Simi, Mitzi Pezes, California Peptide Research
Flash chromatography is a fast and cost-efficient approach to purify synthetic peptides and other small molecules. Using flash chromatography can quickly increase overall purity of peptides prior to the next amino acid addition or final polishing on preparative HPLC.
Read more.
Featured Article

ANATEL Clean-In-Place (CIP) Application Note
By Tony Harrison, subject matter expert, UK British Standards Institute
Frequently, CIP processes are validated and verified using laboratory grab sample analysis. The disadvantages of using this on an ongoing basis is that the number of grab samples required can be costly in terms of time and laboratory instrument reagents. Read more.

Featured Multimedia

Using High Throughput (HT) Methods To Accelerate DOE Video

High throughput experimentation (HTE) was used in this case study in concert with DOE methodology to study the mass recovery of a basic therapeutic protein (pI 9.2-9.5) using a hydrophobic cation exchange mixed mode resin.

Featured Product
In-Line Conditioning For Process Chromatography In-Line Conditioning For Process Chromatography
GE Healthcare has delivered a wide range of IC systems for researchers and process engineers who need to formulate buffer solutions precisely at the time of use using stock solutions of the buffer components, providing a reproducible, fully automated IC process.   Read more.
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