Flash chromatography is a fast and cost-efficient approach to purify synthetic peptides and other small molecules. Using flash chromatography can quickly increase overall purity of peptides prior to the next amino acid addition or final polishing on preparative HPLC. Read more.
ANATEL Clean-In-Place (CIP) Application Note
By Tony Harrison, subject matter expert, UK British Standards Institute
Frequently, CIP processes are validated and verified using laboratory grab sample analysis. The disadvantages of using this on an ongoing basis is that the number of grab samples required can be costly in terms of time and laboratory instrument reagents. Read more.
High throughput experimentation (HTE) was used in this case study in concert with DOE methodology to study the mass recovery of a basic therapeutic protein (pI 9.2-9.5) using a hydrophobic cation exchange mixed mode resin.
In-Line Conditioning For Process Chromatography
GE Healthcare has delivered a wide range of IC systems for researchers and process engineers who need to formulate buffer solutions precisely at the time of use using stock solutions of the buffer components, providing a reproducible, fully automated IC process. Read more.