Emflon® HTPFR Membrane Filter Cartridges

Emflon HTPFR filter cartridges are specifically designed for the sterile filtration of air and gas and vent service in critical, high-temperature, ozonated-water venting and oxygen-enriched air applications in the biopharmaceutical and biotechnology industries.

Emflon HTPFR filter cartridges are specifically designed for the sterile filtration of air and gas and vent service in critical, high-temperature, ozonated-water venting and oxygen-enriched air applications in the biopharmaceutical and biotechnology industries. High-temperature applications include autoclave, fermentation inlet air, aseptic packaging/blow-fill-seal and hot Water For Injection (WFI) tank vents. Oxygen enrichment of air is common in fermenter or bioreactor applications where improved aeration enables higher product yield. They incorporate a double-layer (0.2 µm) of inherently hydrophobic, Pall-manufactured polytetrafluoroethylene (PTFE) membrane. The polypropylene hardware is specially formulated with protective anti-oxidants and the filter’s support and drainage layers are made of polyphenylsulphide polymer to minimize combustibility. Oxidation-resistant membrane and cartridge components allow extended use in air/vent service up to 100°C and for shorter periods up to 120°C.

Features

• Suitable for Water Intrusion Test (WIT) using water
• Proprietary, Pall-manufactured PTFE membrane
• Oxidation-resistant materials of construction
• Validated with B. diminuta at >10⁷ cfu/cm² effective filtration area per modified ASTM 838-05 standard
• Aerosol bacteriophage-challenge tested with MS2 bacteriophage
• Sodium chloride aerosol-challenged for particle removal to 0.003 µm
• Multi-cycle autoclave and in-situ steam challenged in forward and reverse direction
• High flow rates and low pressure drops
• Part number and serial number laser-etched and encoded in 2D laser-etched matrix
   

Benefits

• No alcohol required
• Subject to rigorous Pall manufacturing and quality controls; secure supply source
• Long service life in air/vent applications even at elevated temperatures, recommended for oxygen aeration applications and on ozonated water tanks
• Provides sterile air under dry conditions, meets cGMP sterilizing-grade filter requirements Guidance for Industry Sterile Drug Products Produced by Aseptic Processing (September 2004)
• Ensures viral safety, mitigates risk of virus contamination from aerosol sources
• Efficient: demonstrates high aerosol particle removal efficiency (filters rated at 0.003 µm in gas)
• Robust construction, offers enhanced steaming resistance
• Economical: allows use of small filtration systems, reduces installation and operational costs
• Ease of Use: information can be easily read or scanned with a barcode reader