How To Simplify Virus Production Process Scale-Up?
Discover how to efficiently scale-up vaccine manufacturing processes by moving from 2-D vessels to the Integrity® iCELLis® series of single-use fixed-bed bioreactors. Learn about results achieved for several virus production process developments and how the fixed-bed design of the iCELLis bioreactor enables high cell densities to be achieved. Click here.
By Iftekhar Ahmed, Ben VanderPlas, and Stu Krupnick, ThermoSafe, Sonoco Protective Solutions
Bulk transportation of temperature-sensitive pharmaceuticals and biologics has become a common practice due to complex global supply chains. This imperative has prompted pharmaceutical companies to look at more efficient and economical means of temperature-controlled distribution. Passive packaging systems are one of the proven and repeatable methods for international bulk shipments of temperature-sensitive products.
By Jean Bédard, President and CEO, Infitrak
Have you ever conducted an analysis of the product loss and maintenance costs around your own refrigeration equipment? If not, let's look at a scenario, based on actual customer data, to help determine what improperly monitored temperatures are really costing you.
By Leon VanWormer, MBA, Sartorius Stedim Biotech
Although traditional stainless-steel equipment has lost a great deal of market penetration to single-use alternatives over the past decade, there still is a need for quality filter cartridge systems for sterilizing and polishing filtration processes.
By Michael Gotz, QuickSTAT
In the previous blog post, "Infectious Biologicals Category A and B — Classification Guidelines," I provided definitions of infectious biologicals Category A and B, and some basic guidelines on how to classify your shipments. These definitions are clear and helpful when you know that your shipment contains pathogens. In that case, it is either on the list for Category A, or if it is not, then it is classified as Category B.
By George Botsakos, Senior Director and Life Sciences R&D Leader, Cognizant Business Consulting
In the face of growing challenges, PV leaders must focus on collaboration, globalization, capacity management, transparency, and integrating and analyzing information.
By Brad Larson, Peter Banks, Nicolas Pierre, and Grant Cameron, BioTek Instruments, Inc.
Three-dimensional (3D) cell culture is poised to meet the need for a more in vivo-like cellular model with which to test large and small molecules. This is accomplished by providing a method that allows for the reorganization of cells into a format which re-establishes the necessary cellular architecture and communication networks seen in normal tissue. Recently, a methodology has been put forth that incorporates a simplified procedure for the creation of a cell and collagen hydrogel mix. The inclusion of appropriate liquid handling instrumentation can further simplify the process and ensure the generation of accurate, robust results.
IBC's Cell Therapy Bioprocessing conference (October 21 and 22, 2013, in Bethesda, MD) offers the latest data on the industry pipeline, business models, metrics, and trends to advance your cell therapy program toward commercial success. Download the Brochure