By Eric Langer, President and Managing Partner, BioPlan Associates, Inc.
How the most critical innovations will affect the industry future, with the efforts to reduce the costs of manufacturing a biologic, according to the 10th Annual Report and Survey of Biopharmaceutical Manufacturers.
By Dr. Reno Nguyen, Scott Anderson, Dr. Chitra Sundararajan, Dennis McCreary, and Dr. Jochen Saar, Grace
Peptide therapeutics have been recognized as delivering the best of both worlds in terms of small molecule synthesis efficiency and biologics efficacy and reduced toxicity. However, challenges in mass production and low oral availability have historically made them less than ideal drug candidates.
By Richard Mirro, Eppendorf Inc.
This application report presents a simple protocol for achieving high-density culture of Sf-9 insect cells using a New Brunswick benchtop, autoclavable, stirred-tank bioreactor.
By Dan Catizone, QuickSTAT
Much has been written about cold chain logistics; however, successful and efficient planning still presents many challenges. One of them is choosing an appropriate packaging system. (You can learn more about overcoming cold chain logistics challenges in our white paper, "Best Practices in Cold Chain Logistics Planning.")
By Jenny Sprung, Labconco Product Manager
Lyophilization is a useful tool in the manufacturing of prescription drugs, both generic and name brand. The article "Freeze Drying Generics: Cost Advantages and Considerations" covers the pros and cons of lyophilization in the pharmaceutical sector, but doesn’t offer advice on how to optimize the lyophilization process. The additional information below this excerpt gives context to the author's comments.