The SARTOFLOW® Advanced is a modular benchtop crossflow system optimized for ultrafiltration, microfiltration and diafiltration. Its unique compact design has an ultra low loop volume of ~200 ml, making it possible to concentrate small process batches.
This system can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes and can be linearly scaled up from 0.1 to 2.1 m2 of membrane area, since all Sartocon® crossflow cassettes have the same hydrodynamic flow path length.
Change On The Horizon For Biomanufacturing By Eric Langer, BioPlan Associates, Inc
A leading indicator as to where the global bio industry is headed, geographically, is where its global vendors are setting up shop. In our 8th Annual Report and Survey of Biopharmaceutical Manufacturing, along with 352 biomanufacturers, we also surveyed 186 suppliers to the industry.
Trends In The Manufacturing Of Viral Gene Therapeutics And Next-Generation Vaccines By Jeff Strobel, SAFC Carlsbad
Much of the technology used for the current manufacturing of viral vaccines has its roots in discoveries from the gene therapy industry. Gene therapy, or more correctly, gene transfer, is a catch-all phrase for those products which use a viral vector, plasmid, or cell as a delivery vehicle for a gene product.
The New Vaccines Business
Vaccines, the drugs that shaped the pharmaceutical industry of the 1970s and 1980s, were largely abandoned by most major drug companies in the mid 1990s. By the early 2000s, there were only five major vaccine manufacturers in the world: Merck, GlaxoSmithKline, sanofi-aventis, Novartis, and Wyeth (now Pfizer).
Filtration Processes Applied In Vaccine Production
All vaccines have at least two common elements: they must be immunogenic and they must be produced in a highly purified formable to be safely administered to recipients. Typically, vaccines are produced to treat the general population, however, vaccines can be tailor-made to treat specific individuals.