Newsletter | February 1, 2012

2.1.12 -- Change On The Horizon For Biomanufacturing

Bioresearch Online Newsletter
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The SARTOFLOW® Advanced is a modular benchtop crossflow system optimized for ultrafiltration, microfiltration and diafiltration. Its unique compact design has an ultra low loop volume of ~200 ml, making it possible to concentrate small process batches.

This system can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes and can be linearly scaled up from 0.1 to 2.1 m2 of membrane area, since all Sartocon® crossflow cassettes have the same hydrodynamic flow path length.

Learn more.

Featured Articles

Change On The Horizon For Biomanufacturing
By Eric Langer, BioPlan Associates, Inc
A leading indicator as to where the global bio industry is headed, geographically, is where its global vendors are setting up shop. In our 8th Annual Report and Survey of Biopharmaceutical Manufacturing, along with 352 biomanufacturers, we also surveyed 186 suppliers to the industry.


Trends In The Manufacturing Of Viral Gene Therapeutics And Next-Generation Vaccines
By Jeff Strobel, SAFC Carlsbad
Much of the technology used for the current manufacturing of viral vaccines has its roots in discoveries from the gene therapy industry. Gene therapy, or more correctly, gene transfer, is a catch-all phrase for those products which use a viral vector, plasmid, or cell as a delivery vehicle for a gene product.

Spotlight On Vaccines

Managing Risks Within Platform Processes Through Media Components
A platform process is a set of standardized protocols and reagents that can be used to support a variety of clinical molecules. An enhancement to the platform can be spread across multiple clinical molecules, improving an organization's return on investment.


The New Vaccines Business
Vaccines, the drugs that shaped the pharmaceutical industry of the 1970s and 1980s, were largely abandoned by most major drug companies in the mid 1990s. By the early 2000s, there were only five major vaccine manufacturers in the world: Merck, GlaxoSmithKline, sanofi-aventis, Novartis, and Wyeth (now Pfizer).


Filtration Processes Applied In Vaccine Production
All vaccines have at least two common elements: they must be immunogenic and they must be produced in a highly purified formable to be safely administered to recipients. Typically, vaccines are produced to treat the general population, however, vaccines can be tailor-made to treat specific individuals.


Viral Vaccine Production With VERO Cells In The iCELLis™ Nano Disposable Fixed-Bed Bioreactor
Viral vaccines are usually produced by anchorage-dependent cell lines (e.g. VERO, MRC-5, WI-38 and CEF). At industrial scale, these cells are either cultivated in static mode on multiplate systems, on roller bottles, or on microcarriers (porous or nonporous) in suspension in bioreactors.

Industry News

Genzyme Announces FDA Approval Of New U.S. Manufacturing Plant
FDA Updates TYSABRI Label To Include Anti-JC Virus Antibody Status As PML Risk Factor
FDA Gives Thumbs Down To Progesterone Vaginal Gel
FDA Lifts HOld On Insmed's ARIKACE®
Kaluza 1.2 Cytometry Software Provides Speed, Enhanced Ease Of Use
IDT Genome-Wide qPCR Primers Ideal For Use With Intercalating Dyes
BioTek's 405 Touch Redefines Microplate Washing
Productivity Gains Using Mastersizer 3000 Add Value In Raw Material Testing
BioLineRx Signs Exclusive License Agreement For BL-8020 Oral Treatment For Hepatitis C
Medgenics Receives Allowance For Key European Patent
View more headlines

Bulletin Board

Webinar: Membrane Chromatography — A Flexible Solution To High-Speed Contaminant Clearance
Webinar: Membrane Chromatography — A Flexible Solution To High-Speed Contaminant Clearance
February 16, 2012 | 7:00 AM PST | 10:00 AM EST | 3:00 PM GMT

This webinar will provide the basic principles of membrane chromatography and illustrate specific customer applications of how this technology, when incorporated into the process, saves time and cost.

Industry Event

BioNetwork East
March 5 to 7, 2012 | Miami, FL
Enter code BEVERT to receive 25% off the full price.

Featured Products And Services

cGMP Biologics Manufacturing Services
cGMP Biologics Manufacturing Services

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Therapure Biopharma Inc.

ProteOn XPR36™: Assay Development And Optimization
ProteOn XPR36™: Assay Development And Optimization

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Bio-Rad Laboratories, Inc.

Seed Expansion And Cell Banking System
Seed Expansion And Cell Banking System

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Refine Technology, LLC

TruTorr Single-Use Sensor
TruTorr Single-Use Sensor

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Finesse Solutions, LLC

EL406 Combination Washer/Dispenser
EL406 Combination Washer/Dispenser

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BioTek Instruments, Inc.

Metabolic Disorders And Endocrine Clinical Trials
Metabolic Disorders And Endocrine Clinical Trials

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ICON

WakoPURE System
WakoPURE System

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Wako Laboratory Chemicals

MICROLAB NIMBUS Heater/Shaker Package
MICROLAB NIMBUS Heater/Shaker Package

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Hamilton Company

Disposable Capsule Filters For Line Sets And BioContainers
Disposable Capsule Filters For Line Sets And BioContainers

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ZenPure Corporation

Zetasizer Micro V
Zetasizer Micro V

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Malvern Instruments

Solenoid Valves
Solenoid Valves

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B├╝rkert Fluid Control Systems

Process Area Barriers Curtains
Process Area Barriers Curtains

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ILC Dover