Buffer / Media Filtration

3M Purification Inc.’s LifeASSURETM PNA series for media filtration filters help bioprocess, pharmaceutical, biologicals, and diagnostic reagent processors meet high standards for microorganism and fine particle control. LifeASSURETM PNA series filters feature a unique asymmetric polyethersulfone (PES) membrane with proprietary Advanced Pleat Technology (APT) construction. This design results in a robust filter that is optimized for both long service life and fast flowing applications, while providing 0.2 µm or 0.45 µm rated filtration for superior reduction of microorganisms.

The filter membrane and cartridge design innovations result in a highly durable filter cartridge, capable of secure operation through numerous cycles of steam sterilization and chemical-based cleaning and sanitation protocols. LifeASSURE PNA series filters offer processors a complete solution for rigorous contaminant control while maintaining long service life and low operating costs. 

Features & Benefits

• Hydrophilic asymmetric polyethersulfone membrane - Ensures easy wet-out and low protein binding while providing fast flow rates Applications
• Advanced Pleat Technology design - Allows maximum fluid and contaminant access to filter surface area for high throughput
• 100% Integrity tested prior to release - Ensures consistent performance to specification
• 21 CFR materials of construction - Passes USP Biological Reactivity for Class VI Plastics Test
• Regulatory Support File - Eases validation and regulatory submissions

Applications

• Media and fermenter feed streams
• Serum and blood fractions  
• Diagnostics
• Biologicals 
• Chromatography column protection
• Cell culture fluids 
• Large volume parenterals (LVP)
• Reagents and Buffers
• Ophthalmics
• High purity DI water and WFI systems
• Bulk pharmaceutical chemicals
• Orals and topicals