Increase Purification Productivity With Automated Vacuum Filtration Technology

Purification of biomolecules requires a series of steps involving the removal of contaminants, desalting, buffer exchange, and sample concentration.

Automated vacuum filtration technology for purification has a number of advantages in simultaneous processing of multiple samples, speed and consistency, as well as retaining the biological activity of the biomolecule of interest.

For many downstream applications, such as sequencing or hybridization, PCR-amplified DNA has to be purified to remove primers or other components from the reaction mix. To increase productivity of vacuum filtration protocols, the HydroFlex automates key process steps including self-sealing of filtration plates, online vacuum control, fast dispensing of wash buffers, and many more.

Additionally, the HydroFlex offers a tuneable vacuum range from -50 mbar to -850 mbar relative pressure, making it the solution of choice for high-vacuum applications such as automated PCR-cleanup, as well as for low-vacuum applications such as processing of bead-based assays.