Newsletter | June 23, 2014

06.23.14 -- AstraZeneca And ADDC Announce Drug Development Collaboration

Bioresearch Online Newsletter

Upcoming Webinar

Transform And Redefine Biopharmaceutical Purification With Innovative Process Solutions

In this webinar you will learn about the Emphaze AEX Hybrid Purifier — a multimechanism clarification device that embodies the philosophy of innovation necessary to transform and redefine the mAb purification process.

Featured Focus

Lessons Learned Help Pfizer Accelerate Biotherapeutic Development
By Rob Wright
Six of the seven blockbuster biotherapeutics belonging to Big Pharma have roots to small biotechs. So too does Tim Charlebois, Ph.D., VP of technology and innovation strategy within Pfizer’s biotherapeutics pharmaceutical sciences (BTx Pharm Sci).

Featured Content

Application Note: Minimizing Purification Bottlenecks While Achieving Maximum Sample Recovery
By Scott Anderson, Kathy Lawrence, Dennis McCreary, and Melissa Wilcox, Grace
By using the RevealX detection technology of the Reveleris system, which independently triggers fraction collection from multiple detectors including UV and ELSD, this work will demonstrate that these bottlenecks can be reduced or eliminated without reducing the recovery of compounds of interest.


Application Note: Process-Scale Antibody Purification
By GE Healthcare Life Sciences
This application note describes a three-step purification process of a domain antibody (Dab) expressed in the periplasm of E. coli. First, a capture step using Capto L was used to reduce E. coli. host cell proteins (ECP) and endotoxin levels. Next, a polishing step using Capto MMC ImpRes further reduced ECP and endotoxin levels at yields of > 86%. Finally, Capto adhere ImpRes was run in flow-through mode to render product with undetectable endotoxin levels and ECP content of < 10 ppm.


White Paper: Mixing Predictions Without A Mixer
By ASI Life Sciences
The purpose of the Computational Fluid Dynamics (CFD) Study was to predict the mixing performance of ASI's imPULSE Single-Use Mixing System across a range of small, medium, and large-scale vessels and fluid viscosities.


Case Study: Precise Cold Chain Logistics Supports Global Study Of Heart Disease
By Marken
The challenge involved the precise cold storage temperatures (between 2°C to 8°C) required to assure the integrity of the strips during the transfer and storage of the product to various sites around the globe.

Most Recent News

Pfizer To Front $80 Million In Cellectis Deal
FDA OKs Largest Biomanufacturing Facility in U.S.
AstraZeneca And ADDC Announce Drug Development Collaboration
Ziarco Receives £1.7M Grant From UK's TSB For ZPL-389 Phase 2A
Inovio Expands License Agreement With University of Pennsylvania
View more headlines

 

Upcoming Training

 


The Future Of Biosimilars: Addressing Regulatory Challenges
Date: Thursday, June 19, 2014 • Time: 1 pm to 2:30 pm EST

Featured Downloads

BalanCD CHO Growth A Cell Culture Medium Brochure
BalanCD CHO Growth A is a chemically defined growth medium, containing no animal derived components.

Cargo Companion: Air Cargo Tracking Solution Brochure
The commercial air cargo industry's most comprehensive tracking solution provides location and temperature information for your time-critical, high-value and temperature-sensitive cargo.

Standard Practice Digital File Protocol
The Standard is designed to be of interest to all professionals who contribute to digital file creation.

Active Cold Chain Services: With You Every Step Of The Way
At the heart of the Envirotainer solution is Active Cold Chain Services, where customers can take advantage of the company's knowledge and expertise in healthcare transportation by working with a dedicated team of specialists.
Browse the download library

Featured Multimedia

Nuvia Q And S High-Capacity Ion Exchangers For Biotherapeutic Purification Video
Bio-Rad now offers two very-high-capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

Bulletin Board

Successful Implementation Of Automation In Single-Use Bioprocessing
This webinar will look at a project to automate a single-use, final bulk filtration and dispense processing step at Fujifilm Diosynth Biotechnologies, a biopharmaceutical contract manufacturing organization. The decision-making process used to proceed with the project, the project execution, and the outcomes of the project will all be described.

Featured Products And Services

Temperature-Sensitive Shipments: RKN t2 Container
Temperature-Sensitive Shipments: RKN t2 Container

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Envirotainer

Chromatography Vials
Chromatography Vials

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WHEATON

Pegasus SV4 Virus Removal Filters
Pegasus SV4 Virus Removal Filters

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Pall Life Sciences - BioPharmaceuticals

Syringes And Needles: Precise Fluid Measuring Devices
Syringes And Needles: Precise Fluid Measuring Devices

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Hamilton Company

Sterilizing-Grade Filters: Small Molecule And API Applications
Sterilizing-Grade Filters: Small Molecule And API Applications

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3M Purification

Bioprocess/Bulk Media Containers
Bioprocess/Bulk Media Containers

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ASI Life Sciences

MET ONE HHPC 2+ Handheld Particle Counter
MET ONE HHPC 2+ Handheld Particle Counter

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Beckman Coulter Life Sciences

Sartocheck 4 Plus Bag Integrity Tester
Sartocheck 4 Plus Bag Integrity Tester

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Sartorius Stedim Biotech