Newsletter | March 26, 2014

03.26.14 -- Animal Testing Reduced By Creation Of New Drug Research Technology

Bioresearch Online Newsletter
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Bioprocess Optimization By MS Integration
With its comprehensive data management the Eppendorf DASware® Software Suite allows seamless integration of a Mass Spectrometer (MS) enabling online calculation of key fermentation operating values.
The following application note describes how MS integration was implemented to optimize an isobutanol production process. Using OPC communication real-time MS results were sent to the DASGIP® Control System, charted and transferred to the data historian with synchronized time stamps. Download application note.
Featured Focus: Upstream
How To Analyze Nuclear Stained Cells Using A Multimode Microplate Reader With DAPI-Stained Cells
By Paul Held Ph.D., and Peter Banks, Ph.D., BioTek Instruments, Inc.
This application report presents a simple protocol for achieving high-density culture of Chinese hamster ovary (CHO) cells using a New Brunswick™ benchtop, autoclavable, stirred-tank bioreactor.
APPLICATION NOTE: Introduction To CHO Culture In A Stirred-Tank Bioreactor
By Richard Mirro, Eppendorf Inc.
This application report presents a simple protocol for achieving high-density culture of Chinese Hamster Ovary (CHO) cells using a New Brunswick™ benchtop, autoclavable stirred-tank bioreactor.
BROCHURE: BalanCD Chemically Defined Growth And Feed Media
BROCHURE: Small Vessel, Single-Use Bioreactor For A Scale-Down Model
PRODUCT: GGsTop: Highly Selective Enzyme y-Glutamyl Transpeptidase (GGT) Inhibitor
PRODUCT: ForteBio Dip And Read Biosensor
PRODUCT: Chromatography Vials
» Downstream
Q&A: What Lies Ahead For Single Use In Liquid Handling Processes?
A Q&A with Brandon Pence, Thermo Scientific Cell Culture and Bioprocessing


APPLICATION NOTE: Integration Of A Single-Use Platform Process Within An Innovative Facility Design
By R. Barry Holtz, Ph.D., President, G-Con Manufacturing, LLC; and Dennis Powers, Director, Integrated Solutions North America, Sartorius Stedim North America, Inc.
With the age of the blockbuster drug passing, the business model for the biopharmaceutical industry is changing.
CATALOG: Chromatography Essentials
VIDEO: Genderless Sterile Connectors For Single-Use Bioprocessing Applications
DATASHEET: Take Product Samples With Minimal Effort: Three60 Sampling System
By ASI Life Sciences
PRODUCT: Macro-Prep Methyl HIC Media
PRODUCT: Chromatography ÄKTA Ready And ReadyToProcess Columns
» Supply Chain Integrity
APPLICATION NOTE: How To Avoid FDA 483s For Temperature, Humidity, And Other Controlled Environments
WHITE PAPER: What's The Impact Of Big Data In The Cold Chain?
CASE STUDY: When It Comes To Shipping Perishables, It's The Little Things That Make A Big Difference
VIDEO: AcuTemp Passive Shippers Video
PRODUCT/SERVICE: Via Prequalified Universal Insulated Shipper
» Quality/Regulatory
BROCHURE: VHP M100 Biodecontamination Closed-Loop System
PRODUCT: Integrity Bioreactors
PRODUCT: miVac SpeedTrap Frost-Free Cold Trap
PRODUCT: Dissolved Oxygen Optical Sensors
PRODUCT: Process Area Barriers Curtains
PRODUCT: Bioprocess Monitoring Tools
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High-Capacity Centrifuge Offers High-Performance With High Batch Processing Volume

Combination Products: Clinical Benefits, Regulatory Issues And Manufacturing Challenges
Date: Thursday, April 3, 2014 • Time: 1pm – 2:30pm EST

Source Data Review (SDR) vs. Source Data Verification (SDV) — A Site Monitoring Best Practices Update
Date: Friday, April 11, 2014 • Time: 1pm – 2:30pm EST

Root Cause Analysis for GCP — A Risk Action Plan Guide
Date: Tuesday, April 15, 2014 • Time: 1pm – 2:30pm EST
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