By Paul Held Ph.D. and Peter Banks, Ph.D., BioTek Instruments, Inc.
The imaging and analysis of fluorescently stained cells has traditionally been accomplished using manual microscopic methods with low numbers of samples, while the analysis of higher sample numbers requires the use of very expensive dedicated microscopes.
By Mark C. Arjona, Catherine Nguyen, Jenny Y. Bang, Tom Fletcher, and Jessie H.T. Ni
In the production of biologics, various development activities require different medium requirements, calling for multiple media.
By Brian Garrett, LEED Green Associate and Product Specialist, Labconco Corporation
One of a biosafety officer or laboratory manager's most vital functions is that of performing risk assessments. This multistep process becomes the backbone of a microbiology laboratory's biosafety plan, operating procedures, and, if done early, facility design.
By Dr. Frank Westad, Chief Scientific Officer, CAMO Software
Multivariate statistical process monitoring (MSPM) has been established as a valuable tool for ensuring reliable product quality in the process industry. However, many organizations today are still not fully utilizing its potential to make significant improvements in their production environment.
By Tim Russell, TSI Incorporated
A facility monitoring system (FMS) is a process monitoring tool that collects data from sensors such as optical particle counters, differential pressure sensors, and temperature probes in real time.
By Jeff Clark, 7P Solutions, LLC
Quality is certainly not new terminology in the pharmaceutical industry. However, I believe it is a term that is sometimes used too loosely within the pharmaceutical time and temperature supply chain.
By Nick Hutchinson, Parker domnick hunter Process Filtration
Crossflow filtration used in bioprocesses is typically either microfiltration to clarify process streams or ultrafiltration to concentrate and diafiltrate the biopharmaceutical molecule.
By Lori Clapper A Q&A With Brent Todd, ATMI Life Sciences.
Q: Can you compare pressure decay and helium integrity testing?
A: Most bags today are tested by pressure decay, which is the industry standard, and it works fine — but there are some limitations to this technology. As customers begin using single-use assemblies further and further downstream, they have a need to increase their assurance of integrity and sterility in their single-use manifolds, bags, etc. That is why ATMI developed the innovative helium integrity tester (HITTM) — to do just that.