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Achieving Improved Productivity In Peptide Purification
By Dr. Reno Nguyen, Grace Process Purification Specialist |
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Peptide therapeutics have been recognized as delivering the best of both worlds in terms of small molecule synthesis efficiency and biologics efficacy and reduced toxicity. However, challenges in mass production and low oral availability have historically made them less than ideal drug candidates.
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Featured Articles |
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Benefits Of A Revised Approach To Anion Exchange Flow-Through Polish Chromatography
By Shelly Cote Parra, Christine Gebski, BioPharm International Supplements
Anion exchange (AEX) products are commonly used as a polish step in product flow-through (FT) mode to bind impurities. In this article, a novel approach to AEX FT using a short, 5-cm length, packed-bed format with a faster operating flow rate is explained. Read more.
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Implementing Online Nano-UHPLC Technology For Improved Productivity In Proteomics Applications
By Lasse Gaarde Falkenby, Ole Hørning, Christian Ravnsborg, et al., Thermo Fisher Scientific
Proteomics laboratories have traditionally relied on nano high performance liquid chromatography (nano-HPLC) for their analyses. However, this technique is not powerful enough to meet the separation requirement of proteomics applications, considerably reducing the number of protein and peptide identifications that can be performed. Read more.
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Featured Application |
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Filtration Processes Applied In Vaccine Production
All vaccines have at least two common elements: they must be immunogenic, and they must be produced in a highly purified form, able to be safely administered to recipients. Typically, vaccines are produced to treat the general population; however, vaccines can be tailor-made to treat specific individuals. Read more. |
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