A Rapid, Sample-Safe, Evaporative Technique For Preparation Of DNA And Oligonucleotide Samples

By Tim Watts, Rob Darrington and Ian Whitehall

The difficulties of concentration of oligonucleotides and especially tagged oligonucleotides are well documented in the literature. Adverse conditions can damage the sample, and in some cases totally degrade it. When sourcing a concentration method for their microtitre plates containing oligonucleotides (oligos), researchers at Wellcome Trust Centre for Human Genetics (WTCHG) were careful to choose an evaporator system that would not only provide fast drying, but also take good care of their samples.