Frequently there is reliance on established purification steps such as ion-exchange chromatography to remove endotoxin, though separating LPS from proteins can be very challenging — and is not always achievable by this approach. This poster describes a novel, nontoxic, and highly stable synthetic affinity adsorbent (EtoxiClear™) identified for the capture and removal of endotoxin from a wide range of biological products. Read more.
Skid-Mounted Liquid Chromatography Systems
By Mark McGlynn, IPEC
IPEC provided three skid-mounted liquid chromatography systems to Cook Pharmica, located in Bloomington, Indiana. The systems consisted of piping, valves, pumps, filters, bubble traps, and instrumentation, and are suitable for operation under cGMP guidelines. The systems are capable of in-place cleaning and sanitization. Read more.
Thank you for reading Bioresearch Online’s Chromatography Impact. Do you have a topic you would like to see addressed in future issues, or do you have experience with chromatography that you could share? Let us know!