TufRol Polystyrene Roller Bottles

Thermo Scientific NuncTufRol PS Roller Bottles are developed for applications such as industrial scale production of vaccines, monoclonal antibodies and biotherapeutics, providing reliability and reproducabilty necessary for all your cell growth needs.

Thermo Scientific NuncTufRol PS Roller Bottles are developed for applications such as industrial scale production of vaccines, monoclonal antibodies and biotherapeutics, providing reliability and reproducabilty necessary for all your cell growth needs.

The growth environment of the roller bottle is very dynamic when compared to static culture systems. Cells are intermittently bathed in the nutrient media through the continuous, slow rotation of the bottle. For the majority of the cycle that the cells are not submersed, a thin layer of media coats the cells providing an increase in the media surface coverage relative to its volume. This increase in overall growth area, combined with the higher media surface to volume ratio and the gentle agitation, boosts gas exchange and enhances monolayer formation.

Minimize validation of cell culture scale-up processes from plates to flasks to roller bottles by choosing a family of products that utilize polystyrene materials.

• One-piece seamless design: Reduces possibility of leaking through a seam
• Shallow and deep indents: Unique ergonomic design makes the roller bottle excellent for both manual and automated handling
• Proprietary manufacturing process: Greater impact resistance
• Vertical expanded surfaces version: Vertical pleat orientation facilitates emptying and reduces retention of product

Recommended for: Cell Culture Expansion, Vaccine Production, Antibody Production