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From The Show Floor
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The Latest And Greatest In Analytical Science
By Lori Clapper, Editor
The impressive Pittcon exhibition is always a highlight of the conference, and this year was no different. The West Hall of the convention center housed about 950 exhibitors. Although I couldn't visit them all, I managed to navigate my way around the exhibit floor with nearly 10,000 other attendees from 90 countries. The following takes you on a virtual tour of some of the noteworthy exhibits I visited that featured trends in chromatography, the latest in LIMS, as well as tablet testers and centrifugation, to name a few.
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Featured Articles
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Gaps In Traditional Reconstitution Process Filled By Water-For-Injection Syringe
By Mike Schaefers, Ph.D., West Pharmaceutical Services, and Thomas Otto, Vetter
Since the 1930s, pharmaceutical manufacturers have leveraged a method called "lyophilization" to reconstitute into liquid form freeze-dried drugs from which water has been removed. The recent rise in biopharmaceutical drugs has sparked renewed interest in lyophilization as a way to bring injectable biologics and other drugs to market more quickly.
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A Faster And More Efficient Cell Line Development Workflow Using Single Chemically Defined Culture Medium
By Graziella Piras, Michelle Sabourin, Jian Liu, et al, Life Technologies
Cell line development (CLD) is a critical step in the generation of biotherapeutics, but traditional methods are hindered by several pain points, including the lengthy and labor-intensive workflow, lack of reproducibility, and potential protein quality issues. Each step in CLD requires a different culture environment.
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Spotlight On Vaccines
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Cells Disruption By Means Of High-Pressure Homogenization
After the fermentation of cells the culture is processed to separate the cells, by means of a speed centrifuge, in order to concentrate them. The collected cells are resuspended with buffer in order to prepare them for the next unit operation, the high-pressure homogenization used in order to obtain the cells disruption.
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Greater Cold Chain Controls Through Enabling Technology
The term cold chain refers to the time-and-temperature-controlled transportation of temperature-sensitive products from the manufacturer to the end user. The goal of cold chain management is to provide patient safety, product integrity, regulatory compliance, process optimization, and cost optimization.
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Filtration Processes Applied In Vaccine Production
All vaccines have at least two common elements: they must be immunogenic and they must be produced in a highly purified form that is to be safely administered to recipients. Typically, vaccines are produced to treat the general population, however, vaccines can be customized to treat specific individuals.
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Comparison Of Five Cell Culture Media Demonstrating CHO Cell Culture Growth In Batch Or Fed-Batch Process For Commercial Operations
This case study details a two month, four phase project to design chemically-defined feed media that improved two simulated batch processes utilizing products by SAFC, Life Technologies, Thermo Fisher Scientific, and Irvine Scientific.
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QAII Dissolution Systems Suitability Station Brochure
Agilent now offers the market-leading family of dissolution apparatus and sampling systems that pair perfectly with our HPLC and UV systems.
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