Manual: Sartobind® IEX JumboSource: Sartorius Stedim Biotech
Sartobind Jumbo capsules are ion exchange chromatography devices based on macroporous membranes. They can be used for chromatographic separations in the downstream processing of proteins. The ion exchange ligands are coupled to a membrane which is fitted into a plastic housing for quick handling, making ion exchange purification nearly as easy as filtration. Jumbo capsules are constructed with optimized fluid channels. They carry an internal central core to minimize void volume. Fluid models have been developed to reduce the channel width to 3 mm. Capsules with strong basic and strong acidic ion exchange Membrane Adsorber (MA) are available. These products are intended for single use to avoid carryover as well as tedious and costly cleaning validation procedures. However, they can also be reused after cleaning in place. The Jumbo capsules can be applied for contaminant removal from proteins in flowthrough mode (negative chromatography) to bind DNA, residual protein, host cell proteins, endotoxins and viruses, or capture of large proteins as well as dilute proteins in large volumes.
- Simple handling
- Fast operation
- Less buffer consumption
- For capturing and polishing