Purification Technologies

Leading in crossflow filtration, membrane chromatography and virus clearance technologies for state-of-the-art initial recovery and polishing or contaminant removal in biomanufacturing.

UVivatec®
UVivatec® is a state of the art virus inactivation technology with a novel helical reactor design providing uniform irradiation through efficient radial mixing based on dean vortices. UVivatec® is a robust system with single-use modules for inactivation of viruses.
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Phenyl Membrane Adsorber For Bioprocessing
A new phenyl membrane adsorber was designed for purification of biomolecules based on Hydrophobic Interaction Chromatography (HIC) principles. The novel phenyl membrane adsorber features high flow rate and high binding capacity providing a new scalable and disposable tool for purification and separation of biomolecules as well as for polishing applications in the biopharmaceutical industry.
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Sartobind STIC® Membrane Adsorber For High-Salt Polishing
A new salt tolerant membrane adsorber was designed for purification of biomolecules in high salt (>15 mS/cm) conditions. The novel AEX membrane adsorber features high flow rate and high binding capacity for contaminants and provides a new scalable and disposable tool for polishing applications in the biopharmaceutical industry.
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Sartobind® Q SingleSep nano
Sartobind Q nano is a perfect tool for the purification (polishing) of valuable proteins such as monoclonal antibodies. The 1ml bed volume means that that less spiking volume is used during the removal of viruses, DNA, HCP, and endotoxins. Scaling up is easy due to the consistent design and format from the nano-scale to manufacturing-scale Sartobind capsules.
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Sartoflow™ Alpha Plus Crossflow System
The Sartoflow Alpha Plus Crossflow Systems feature the latest advances in crossflow technology from Sartorius. The Sartoflow Alpha Plus is a cGMP system for small scale clinical and process development batches. The Sartoflow Alpha Plus is a modular, semi-automatic system offering numerous standard and optional features. It is designed to be fully SIP.
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Hydrosart® Cassettes for CrossFlow Filtration (TFF)
The Hydrosart membrane is cross-linked cellulose based polymer that is chemically and physically stable in a broad pH range (pH 2.0 to pH 14). The membrane is naturally hydrophilic in nature hence it exhibits extremely low non-specific protein binding and virtually non-fouling characteristics.
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Sartoclear P Depth Filter Sheets
Sartoclear P filter sheets are especially developed for use in the biopharmaceutical industry. They feature cellulose based depth filtration media with highest dirt holding capacity and electrokinetic adsorption. Sartoclear P filter sheets are being used in horizontal filter presses which can be easily adapted to the batch volumes and process conditions on sight.
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Sartoclear P® MaxiCaps®
Sartoclear P® MaxiCaps® are especially developed for cell harvest and clarification of cell culture and microbial fermentation media in biopharmaceutical applications. The products feature cellulose based depth filter media with highest dirt holding capacity and electrocinetic adsorption combined with the advantage of the unique and closed MaxiCap® system.
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Slice Disposable Self Contained Lab Filter
Slice Disposable units are designed for single use applications. Membrane types are available in Polyethersulfone and Hydrosart.
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Polyethersulfone Microfiltration Cassettes
The polyethersulfone membrane (PES) is a membrane polymer that is well established in the biotechnological and pharmaceutical industries. The PES membrane is a stable polymer that features a broad pH and temperature range. Its wide temperature range makes it possible to sterilize the membrane by either steam or autoclaving. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures.
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Polypropylene Microfiltration Cassettes
The Polypropylene membrane is a stable polymer that features a broad pH and temperature range. Polypropylene wide temperature range makes it possible to sterilize the membrane by either steam or autoclaving. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures. Because of these features, Polypropylene is ideal for biological applications. Polypropylene cassettes are available in 0.2 µm.
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Sartobind® SingleSep
Sartobind SingleSep ion exchange capsules are designed to remove contaminants at accelerated flow rates. This is a direct result of negligible mass transfer effects and is made possible by the >3 µm microporous membrane. The design allows for robust chromatographic separations and drastically reduced validation costs. SingleSep capsules are used for DNA removal, host cell protein removal and viral clearance.
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Sartocon® Slice 200 Stainless Steel Holder
The Sartocon Slice 200 system covers the whole range of pharmaceutical and biotechnological crossflow applications like concentration and diafiltration of proteins, vaccines, viruses, antibodies, oligo nucleotides, endotoxin removal etc. The system is suitable for cell harvesting and clarification processes.
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Sartocon® Slice Stainless Steel Holder
The Sartocon Slice system covers the whole range of pharmaceutical and biotechnological crossflow applications like concentration and diafiltration of proteins, vaccines, viruses, antibodies, oligo nucleotides, endotoxin removal etc. The system is suitable for cell harvesting and clarification processes.
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Sartocon® 2 Plus Stainless Steel Holder
The Sartocon 2 Plus stainless steel holder is optimized for the use with up to 10 Sartocon Crossflow cassettes (max. 7 m2). It is designed for medium volume applications from 5 I to 500 I.
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Sartoflow® 10 Stainless Steel Holder
Sartoflow 10 Holder The Sartoflow 10 stainless steel holder is optimized for the use with up to 10 Sartocon Crossflow cassettes (max. 7 m2). It is designed for medium volume applications from 10 l to 500 l.
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Sartoflow® 20 Stainless Steel Holder
The Sartoflow 20 stainless steel holder is optimized for the use with up to 20 Sartocon Crossflow cassettes (max. 14 m2). It is designed for medium volume applications from 200 l to 5000 l.
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Sartoflow® Slice 200 Benchtop Crossflow System
The Family of Sartorius Benchtop Crossflow Systems feature the latest advances in crossflow technology from Sartorius. The Sartoflow Slice 200 benchtop system is designed around our Sartocon Slice 200 (filter area: 200 cm2) cassette and is perfectly suited for R&D, process development, pre-clinical and small pilot lots.
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Sartocon Slice Benchtop System
The Sartocon Slice Benchtop is a basic cost effective Crossflow filtration system for small Micro and Ultrafiltration applications. It is mainly used in Process Development laboratories and pilot plants to run Scale-Up and Scale-Down trials. The system is designed to accommodate upto 5 (0.1m2) Sartorius Sartocon Slice Cassettes.
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Sartocon 2 Plus Benchtop Crossflow System
The Sartocon 2 Plus Benchtop is a basic cost effective Crossflow filtration system for small to intermediate scale Micro and Ultrafiltration pharmaceutical and biotech applications. The Sartocon 2 Plus Benchtop is mainly used in Process Development laboratories and Pilot plants to run small production and clinical lots. The system is designed for membrane areas of 0.4 to 2.5 m2 but can accommodate upto 10 Sartorius Sartocon Cassettes.
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Sartoflow 20 Basic Plus Crossflow System
The Sartoflow 20 System sports the Sartorius Sartoflow 20 cassette holder complete with a hydraulic closure system which redefines ease of use while providing fool proof security. It is supplied complete with valves, gauges, flow meters and safety features like a high pressure switch.
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Sartoflow 10/20 Auto Crossflow System
The Family of Sartoflow Crossflow Systems feature the latest advances in crossflow technology from Sartorius. Our crossflow systems are constructed to hold any cassette. The Sartoflow 10 & 20 are Crossflow filtration systems for intermediate to full scale MF and UF biopharmaceutical applications.
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Virosart® CPV
Virus filtration with Virosart® CPV is an integral part of the 3-step viral clearance technology platform of Sartorius featuring virus filtration, virus inactivation, and virus adsorption. Virosart® CPV has been especially developed for the removal of relevant, as well as adventitious viruses from the biopharmaceutical feed stream.
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SARTOFLOW® Advanced
The SARTOFLOW® Advanced is a modular benchtop crossflow system optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins.
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Sartocon® ECO
The New ECO cassettes from Sartorius are made with the same premium Hydrosart membrane as the Standard Hydroasr cassettes but have an enhanced retentate flow geometry to increase permate flux rates at 1/3rd to 1/2 the standard Sartorius cassettes.TFF rate. There is also 26% increased membrane area per cassette.
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Albumin Ultrafiltration Cassettes "PESU-MAX"
The PESU-MAX membrane is made out of polyethersulfone (PESU). This membrane polymer is well established in the biotechnological and pharmaceutical industries. The PESU-MAX cassette, is designed for use in the blood market specially for ALBUMIN rejectable applications.
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Polyethersulfone Ultrafiltration Cassettes
The polyethersulfone membrane (PES) is a membrane polymer that is well established in the biotechnological and pharmaceutical industries. The PES membrane is a stable polymer that features a broad pH and temperature range. Its wide temperature range makes it possible to sterilize some of the membrane by either steam or autoclaving. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures.
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Slice Disposable Self Contained Lab Filter
Slice Disposable units are designed for single use applications. Membrane types are available in Polyethersulfone and Hydrosart.
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